Highlighting the trajectory from intrauterine growth restriction to future obesity

KV Gantenbein, C Kanaka-Gantenbein - Frontiers in endocrinology, 2022 - frontiersin.org
During the last decades several lines of evidence reported the association of an adverse
intrauterine environment, leading to intrauterine restriction, with future disease, such as …

Novel regulators of the IGF system in cancer

C Mancarella, A Morrione, K Scotlandi - Biomolecules, 2021 - mdpi.com
The insulin-like growth factor (IGF) system is a dynamic network of proteins, which includes
cognate ligands, membrane receptors, ligand binding proteins and functional downstream …

Interactions between growth of muscle and stature: mechanisms involved and their nutritional sensitivity to dietary protein: the protein-stat revisited

DJ Millward - Nutrients, 2021 - mdpi.com
Childhood growth and its sensitivity to dietary protein is reviewed within a Protein-Stat model
of growth regulation. The coordination of growth of muscle and stature is a combination of …

Post-natal muscle growth and protein turnover: a narrative review of current understanding

DJ Millward - Nutrition research reviews, 2024 - cambridge.org
A model explaining the dietary-protein-driven post-natal skeletal muscle growth and protein
turnover in the rat is updated, and the mechanisms involved are described, in this narrative …

IGF-1 and IGF-2 as Molecules Linked to Causes and Consequences of Obesity from Fetal Life to Adulthood: A Systematic Review

J Szydlowska-Gladysz, AE Gorecka, J Stepien… - International Journal of …, 2024 - mdpi.com
This study examines the impact of insulin-like growth factor 1 (IGF-1) and insulin-like growth
factor 2 (IGF-2) on various aspects of children's health—from the realms of growth and …

Further evidence that an episode of premature labor is a pathologic state: involvement of the insulin-like growth factor system

P Prasad, R Romero, T Chaiworapongsa… - Fetal diagnosis and …, 2023 - karger.com
Introduction: Approximately 47% of women with an episode of preterm labor deliver at term;
however, their infants are at greater risk of being small for gestational age and for …

Single-Cell Transcriptional Profile Construction of Rat Pituitary Glands before and after Sexual Maturation and Identification of Novel Marker Spp1 in Gonadotropes

QH Huang, GK Zhao, HQ Wang, FH Wei… - International Journal of …, 2024 - mdpi.com
The mammalian pituitary gland drives highly conserved physiological processes such as
somatic cell growth, pubertal transformation, fertility, and metabolism by secreting a variety …

Frequency and Predictive Factors of Hypoglycemia in Patients Treated With rhIGF-1: Data From the Eu-IGFD Registry

P Bang, M Polak, A Bossowski… - The Journal of …, 2024 - academic.oup.com
Abstract Context The European Increlex® Growth Forum Database (Eu-IGFD) is an ongoing
surveillance registry (NCT00903110) established to collect long-term safety and …

Polymorphism of the growth hormone gene GH1 in Polish children and adolescents with short stature

KA Majewska, A Kedzia, P Kontowicz, M Prauzinska… - Endocrine, 2020 - Springer
Purpose Short stature in children is a significant medical problem which, without proper
diagnosis and treatment, can lead to long-term consequences for physical and …

Alteration in the levels of IGF-axis components in small for gestational age neonates

MN Nithya, J Krishnappa, SR Sheela, V Raavi - Gene Reports, 2024 - Elsevier
Abstract Growth hormone (GH)/Insulin-like growth factor (IGF)-axis plays an essential role in
fetal growth and development. The levels of IGF-axis proteins, gene expression, and …