Neuroinflammation is the fundamental immune response against multiple factors in the
central nervous system and is characterized by the production of inflammatory mediators …

Hyperoside is an active ingredient in plants, such as Hypericum monogynum in
Hypericaceae, Crataegus pinnatifida in Rosaceae and Polygonum aviculare in …

Mitragyna speciosa is a medicinal plant with a reputation for treating pains, diabetes as well
as increasing energy and sexual desires. However, there is no scientific evidence to validate …

Accumulating evidence reveals that both inflammation and lymphocyte dysfunction play a
vital role in the development of diabetic nephropathy (DN). Hyperoside (HPS) or quercetin-3 …

Neuroinflammation plays important roles in the pathogenesis and progression of altered
neurodevelopment, sensorineural hearing loss, and certain neurodegenerative diseases …

Alzheimer's disease (AD) is a neurodegenerative disease characterized by amyloid plaques
and tangles that have become the fifth leading cause of death worldwide. Previous studies …

Abstract Ethnopharmacological relevance Huang-Lian-Jie-Du decoction (HLJDD) is a
traditional Chinese formula that is efficacious in treating diabetes mellitus, Alzheimer's …

Increasing data suggest a crucial role of circadian rhythm in regulating metabolic and
neurological diseases, and Bmal1 is regarded as a key regulator of circadian transcription …

Presently, the treatment options for ischemic stroke (IS) are limited due to the complicated
pathological process of the disease. Chuanxiong Rhizome (CR), also known as …

Although diabetic cognitive impairment is one of the most common complications of type 2
diabetes mellitus (T2DM), optimized therapeutic strategies are not available yet …