Natural killer (NK) cells have a crucial role in combating infections and cancers and their
surface receptors can directly recognize and respond to damaged, transformed or non-self …

Review underscores the ubiquitous contribution of IFN-δ to immune responses against
malaria, evidence for its protective role and critical issues relating to its induction. Immune …

There is considerable debate as to the nature of the primary parasite-derived moieties that
activate innate pro-inflammatory responses during malaria infection. Microparticles (MPs) …

Murine models of Plasmodium falciparum malaria may become crucial tools in drug
discovery. Here we show that non-myelodepleted NOD-scid IL2Rγ null mice engrafted with …

Natural killer (NK) cells are large granular lymphocytes that express a diverse array of
germline encoded inhibitory and activating receptors for MHC Class I and Class I-like …

We characterized vaccine-induced cellular responses to rabies virus in naive adult
volunteers. Contrary to current paradigms, we observed potent and prolonged in vitro NK …

Natural killer (NK) cells are important innate effector cells that are well described in their
ability to kill virally-infected cells and tumors. However, there is increasing appreciation for …

Rapid cell-mediated immune responses, characterized by production of proinflammatory
cytokines, such as IFN-γ, can inhibit intraerythrocytic replication of malaria parasites and …

Armed with potent cytotoxic and immunostimulatory effector functions, natural killer (NK)
cells have the potential to cause significant damage to normal self cells unless controlled by …

NK cells play a key role in host resistance to a range of pathogenic microorganisms,
particularly during the initial stages of infection. NK cell interactions with cells infected with …