[HTML][HTML] Long-term comparative efficacy and safety of nivolumab plus ipilimumab relative to other first-line therapies for advanced non-small-cell lung cancer: A …

K O'Byrne, E Popoff, F Badin, A Lee, Y Yuan… - Lung Cancer, 2023 - Elsevier
Objectives To quantify the long-term comparative efficacy and safety of nivolumab in
combination with ipilimumab (NIVO+ IPI) relative to other immunotherapy (IO)-based …

[HTML][HTML] Treatment considerations for patients with advanced squamous cell carcinoma of the lung

ES Santos, E Rodriguez - Clinical Lung Cancer, 2022 - Elsevier
Squamous cell carcinoma (SCC) of the lung has a markedly different molecular profile to
adenocarcinoma of the lung and remains difficult to treat because of the lack of targeted …

[PDF][PDF] Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer

S Mertens, MA Huismans, CS Verissimo, B Ponsioen… - Cell Reports, 2023 - cell.com
Patient-derived organoids (PDOs) are widely heralded as a drug-screening platform to
develop new anti-cancer therapies. Here, we use a drug-repurposing library to screen PDOs …

Association between age and survival trends in advanced non–small cell lung cancer after adoption of immunotherapy

T Voruganti, PR Soulos, R Mamtani, CJ Presley… - JAMA …, 2023 - jamanetwork.com
Importance The introduction of immune checkpoint inhibitors (ICIs) has transformed the care
of advanced non–small cell lung cancer (NSCLC). Although clinical trials suggest …

[HTML][HTML] Real-world effectiveness and safety of nivolumab in patients with non-small cell lung cancer: A multicenter retrospective observational study in Japan

R Morita, K Okishio, J Shimizu, H Saito, H Sakai… - Lung Cancer, 2020 - Elsevier
Objectives To describe the treatment patterns and determine the effectiveness and safety of
nivolumab treatment for non-small cell lung cancer (NSCLC) in real-world setting in Japan …

[HTML][HTML] HALP score and GNRI: Simple and easily accessible indexes for predicting prognosis in advanced stage NSCLC patients. The İzmir oncology group (IZOG) …

ZG Güç, A Alacacıoğlu, ME Kalender… - Frontiers in …, 2022 - frontiersin.org
Objective: The Hemoglobin, Albumin, Lymphocyte, and Platelet (HALP) Score and the
Geriatric Nutrition Risk Index (GNRI) are used as prognostic factors in different types of …

FOXO3-induced oncogenic lncRNA CASC9 enhances gefitinib resistance of non-small-cell lung cancer through feedback loop

Z Bing, J Han, Z Zheng, N Liang - Life Sciences, 2021 - Elsevier
Gefitinib is tyrosine kinase inhibitor of epidermal growth factor receptor, which exhibits
notable clinical efficacy in non-small-cell lung cancer (NSCLC) treatment. However, gefitinib …

Efficacy and safety of nintedanib in patients with non-small cell lung cancer, and novel insights in radiation-induced lung toxicity

S Yan, S Xue, T Wang, R Gao, H Zeng, Q Wang… - Frontiers in …, 2023 - frontiersin.org
Nintedanib is a tyrosine kinase inhibitor of fibroblast growth factor-, vascular endothelial
growth factor-, and platelet-derived growth factor receptors. These three receptors promote …

HALP score and GNRI: Simple and easily accessible indexes for predicting prognosis in advanced stage NSCLC patients. The Izmir oncology group (IZOG) study

Z Guc, A Alacacioglu, M Kalender, U Oflazoglu… - Frontiers in …, 2022 - avesis.deu.edu.tr
ObjectiveThe Hemoglobin, Albumin, Lymphocyte, and Platelet (HALP) Score and the
Geriatric Nutrition Risk Index (GNRI) are used as prognostic factors in different types of …

[HTML][HTML] A systematic review and network meta-analysis of first-line immune checkpoint inhibitor combination therapies in patients with advanced non-squamous non …

T Shao, M Zhao, L Liang, W Tang - Frontiers in Immunology, 2022 - frontiersin.org
Introduction Clinical evidence suggests that first-line immune checkpoint inhibitor (ICI)
combination therapies can improve survival in patients with advanced non-squamous non …