Antifungal Drug Resistance: Molecular Mechanisms in Candida albicans and Beyond
Fungal infections are a major contributor to infectious disease-related deaths across the
globe. Candida species are among the most common causes of invasive mycotic disease …
globe. Candida species are among the most common causes of invasive mycotic disease …
[HTML][HTML] Immune defence to invasive fungal infections: A comprehensive review
B Pathakumari, G Liang, W Liu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
The fungal infections are relatively common in humans that can range from common, mild
superficial infections to life-threatening invasive infections. Most of the pathogenic fungi are …
superficial infections to life-threatening invasive infections. Most of the pathogenic fungi are …
Molecular evolution of antifungal drug resistance
The fungal pathogens Candida albicans, Cryptococcus neoformans, and Aspergillus
fumigatus have transitioned from a rare curiosity to a leading cause of human mortality. The …
fumigatus have transitioned from a rare curiosity to a leading cause of human mortality. The …
Pharmacokinetics of antifungal drugs: practical implications for optimized treatment of patients
R Bellmann, P Smuszkiewicz - Infection, 2017 - Springer
Introduction Because of the high mortality of invasive fungal infections (IFIs), appropriate
exposure to antifungals appears to be crucial for therapeutic efficacy and safety. Materials …
exposure to antifungals appears to be crucial for therapeutic efficacy and safety. Materials …
[HTML][HTML] Functionalized niosomes as a smart delivery device in cancer and fungal infection
P Aparajay, A Dev - European journal of pharmaceutical sciences, 2022 - Elsevier
Various diseases remain untreated due to lack of suitable therapeutic moiety or a suitable
drug delivery device, especially where toxicities and side effects are the primary reason for …
drug delivery device, especially where toxicities and side effects are the primary reason for …
Electrospun nanofibres in drug delivery: advances in controlled release strategies
Emerging drug-delivery systems demand a controlled or programmable or sustained
release of drug molecules to improve therapeutic efficacy and patient compliance. Such …
release of drug molecules to improve therapeutic efficacy and patient compliance. Such …
Alginate nanoparticles as non-toxic delivery system for miltefosine in the treatment of candidiasis and cryptococcosis
CC Spadari, FWMS de Bastiani, LB Lopes… - International journal of …, 2019 - Taylor & Francis
Introduction and objective Previous studies indicate that miltefosine (MFS) may be an
alternative as an antifungal agent; however, it presents several adverse effects. Thus, the …
alternative as an antifungal agent; however, it presents several adverse effects. Thus, the …
Membrane-interacting antifungal peptides
C Struyfs, BPA Cammue, K Thevissen - Frontiers in cell and …, 2021 - frontiersin.org
The incidence of invasive fungal infections is increasing worldwide, resulting in more than
1.6 million deaths every year. Due to growing antifungal drug resistance and the limited …
1.6 million deaths every year. Due to growing antifungal drug resistance and the limited …
New pathogens, new tricks: emerging, drug‐resistant fungal pathogens and future prospects for antifungal therapeutics
J Geddes‐McAlister, RS Shapiro - … of the New York Academy of …, 2019 - Wiley Online Library
Fungal pathogens are a growing threat to public health. As human immunodeficiency
becomes increasingly common, fungal infections are becoming more prevalent. The use of …
becomes increasingly common, fungal infections are becoming more prevalent. The use of …
New facets of antifungal therapy
Invasive fungal infections remain a major cause of morbidity and mortality in
immunocompromised patients, and such infections are a substantial burden to healthcare …
immunocompromised patients, and such infections are a substantial burden to healthcare …