Use of radioactive iodine is an essential adjuvant treatment strategy after thyroidectomy in
patients with differentiated thyroid carcinoma. Although generally safe, radioiodine therapy …

Papillary thyroid carcinoma (PTC) is associated with RET and NTRK1 rearrangements and
BRAF mutations. A series of 60 PTCs collected in a single center from Italian patients were …

We have recently demonstrated that the pyrazolopyrimidines PP1 and PP2 and the 4-
anilinoquinazoline ZD6474 display a strong inhibitory activity (IC 50⩽ 100 n M) towards …

Purpose: A multicenter, open-label, phase II trial was conducted to evaluate the efficacy,
safety, and tolerability of selumetinib in iodine-refractory papillary thyroid cancer (IRPTC) …

Rationale and Objectives Accurate preoperative identification of lateral cervical lymph node
metastasis (LNM) is important for decision-making and clinical management of patients with …

Context Anaplastic thyroid carcinoma (ATC) is an orphan disease and confers a dismal
prognosis. Standard treatment is not established. Objective The aim of this study is to …

The term theranostics is the combination of a diagnostic tool that helps to define the right
therapeutic tool for specific disease. It signifies the “we know which sites require treatment …

Point mutations in BRAF are genetic hallmarks of papillary thyroid carcinoma (PTC). In this
retrospective study, we examined thyroid aspirates and corresponding paraffin-embedded …

The measurement of tumor markers is currently one of the most rapidly growing areas in
laboratory medicine. Lack of sensitivity and specificity preclude the use of most existing …