Reassessing Human Adipose Tissue Adipose tissue can more than double in mass and
then return to baseline. This review discusses the functional roles of human white and brown …

Obesity is one of the major health burdens of the 21st century as it contributes to the growing
prevalence of its related comorbidities, including insulin resistance and type 2 diabetes …

Obesity and overweight have increased at an alarming rate in the world during the last three
decades. Obesity is a crucial factor in the development of metabolic abnormalities, including …

Both glucose and free fatty acids (FFAs) are used as fuel sources for energy production in a
living organism. Compelling evidence supports a role for excess fatty acids synthesized in …

Two serious health conditions, obesity and atopic dermatitis (AD), share some pathological
features such as insulin resistance, leptin resistance and inflammation, and a growing body …

Skeletal muscle (SM) tissue has been repetitively shown to play a major role in whole-body
glucose homeostasis and overall metabolic health. Hence, SM hypertrophy through …

Frailty is a complex condition that emerges from dysregulation in multiple physiological
systems. Increasing evidence suggests the potential role of age-related energy …

Type 2 diabetes mellitus (T2DM) is characterized by impaired insulin secretion on a
background of insulin resistance (IR). IR and T2DM are associated with atherosclerotic …

Context There is evidence demonstrating variation in insulin sensitivity across the menstrual
cycle. However, to date, research has yielded inconsistent results. Objective This study …

Microgravity environments are known to cause a plethora of stressors to astronauts.
Recently, it has become apparent that gut microbiome composition of astronauts is altered …