Despite significant improvements in reperfusion strategies, acute coronary syndromes all too
often culminate in a myocardial infarction (MI). The consequent MI can, in turn, lead to …

Cardiac arrhythmias are a significant cause of morbidity and mortality worldwide, accounting
for 10% to 15% of all deaths. Although most arrhythmias are due to acquired heart disease …

Background: Ischemic heart disease remains a leading cause of death worldwide. In this
study, we test the hypothesis that microRNA-210 protects the heart from myocardial …

There has been considerable progress in engineering cardiac scaffolds for the treatment of
myocardial infarction (MI). However, it is still challenging to replicate the structural specificity …

Abstract Background Long non-coding RNAs (lncRNAs) play a central role in regulating
heart diseases. In the present study, we examined the effects of lncRNA taurine up …

Necrosis is a key factor in myocardial injury during cardiac pathological processes, such as
myocardial infarction (MI), ischemia/reperfusion (I/R) injury and heart failure. Increasing …

Heart disease causing cardiac cell death due to ischemia–reperfusion injury is a major
cause of morbidity and mortality in the United States. Coronary heart disease and …

The cytochrome P450 monooxygenase system (CYP) is a multigene superfamily of
enzymes, which are important in the metabolism of foreign and endogenous compounds …

Endothelial dysfunction, a hallmark of vascular disease, is restored by plasma high-density
lipoprotein (HDL). However, a generalized increase in HDL abundance is not beneficial …

Approximately 7 million people are affected by acute myocardial infarction (MI) each year,
and despite significant therapeutic and diagnostic advancements, MI remains a leading …