The idea of using chitosan as a functional delivery aid to support simultaneously PRP, stem
cells and growth factors (GF) is associated with the intention to use morphogenic …

Significant advances in cellular reprogramming technologies and hematopoietic
differentiation from human pluripotent stem cells (hPSCs) have already enabled the routine …

Despite our growing understanding of embryonic immune development, rare early
megakaryocytes (MKs) remain relatively understudied. Here we used single-cell RNA …

The production of megakaryocytes (MKs)—the precursors of blood platelets—from human
pluripotent stem cells (hPSCs) offers exciting clinical opportunities for transfusion medicine …

Aim: This review of the literature, and the authors' own decade of experience with lutetium-
177-octreotate-capecitabine±temozolomide peptide receptor radionuclide therapy (PRRT) …

Stem cell technology holds great promise for transfusion medicine, and generation of
platelets from stem cells would be transformative. Platelet transfusions are life saving for …

Congenital amegakaryocytic thrombocytopenia (CAMT) is caused by the loss of
thrombopoietin receptor–mediated (MPL-mediated) signaling, which causes severe …

Background Although airborne fine particulate matter (PM) pollution has been demonstrated
as an independent risk factor for pulmonary and cardiovascular diseases, their currently …

Thrombocytopenia has long been recognized as a significant problem of cancer therapy, but
there is still lack of consensus about the optimal approach to prophylaxis and/or treatment of …

Platelet-to-platelet aggregation is critical to the formation of hemostatic thrombi which limit
bleeding following vascular injury and also contributes to obstructive thrombi in acute …