[HTML][HTML] Mycobacterium tuberculosis and Human Immunodeficiency Virus Type 1 Cooperatively Modulate Macrophage Apoptosis via Toll Like Receptor 2 and …
The emergence of drug resistant strains of Mycobacterium tuberculosis (M. tuberculosis)
together with reports of co-infections with the human immunodeficiency virus (HIV) has …
together with reports of co-infections with the human immunodeficiency virus (HIV) has …
The dysfunctional innate immune response triggered by Toll‐like receptor activation is restored by TLR7/TLR8 and TLR9 ligands in cutaneous lichen planus
R Domingues, GC de Carvalho… - British Journal of …, 2015 - academic.oup.com
Background Lichen planus (LP) is a chronic inflammatory mucocutaneous disease. Toll‐like
receptors (TLRs) bind numerous exogenous and endogenous antigens by recognizing …
receptors (TLRs) bind numerous exogenous and endogenous antigens by recognizing …
[HTML][HTML] Association of maternal factors and HIV infection with innate cytokine responses of delivering mothers and newborns in Mozambique
Maternal factors and exposure to pathogens have an impact on infant health. For instance,
HIV exposed but uninfected infants have higher morbidity and mortality than HIV unexposed …
HIV exposed but uninfected infants have higher morbidity and mortality than HIV unexposed …
[HTML][HTML] Impaired CD8+ T cell responses upon Toll-like receptor activation in common variable immunodeficiency
C de Lollo, D de Moraes Vasconcelos… - Journal of translational …, 2016 - Springer
Background Infections caused by bacteria or viruses are frequent in common variable
immunodeficiency (CVID) patients due to antibody deficiencies, which may be associated …
immunodeficiency (CVID) patients due to antibody deficiencies, which may be associated …
Candidate drug replacements for quinacrine in cutaneous lupus erythematosus
D Yan, R Borucki, RD Sontheimer… - Lupus Science & …, 2020 - lupus.bmj.com
Cutaneous lupus erythematosus (CLE) is a disfiguring and potentially disabling disease that
causes significant morbidity in patients. Antimalarials are an important class of medication …
causes significant morbidity in patients. Antimalarials are an important class of medication …
[HTML][HTML] Upregulation of innate antiviral restricting factor expression in the cord blood and decidual tissue of HIV-infected mothers
Programs for the prevention of mother-to-child transmission of HIV have reduced the
transmission rate of perinatal HIV infection and have thereby increased the number of HIV …
transmission rate of perinatal HIV infection and have thereby increased the number of HIV …
[HTML][HTML] Toll-like receptor agonists partially restore the production of pro-inflammatory cytokines and type I interferon in Sézary syndrome
KCG Manfrere, MP Torrealba, DR Miyashiro… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Sézary syndrome (SS) carries a poor prognosis, and infections represent the most frequent
cause of death in SS patients. Toll-like receptors (TLRs) are a family of innate immune …
cause of death in SS patients. Toll-like receptors (TLRs) are a family of innate immune …
The next generation of HCV vaccines: a focus on novel adjuvant development
K Kardani, SM Sadat, M Kardani… - Expert Review of …, 2021 - Taylor & Francis
Introduction Considerable efforts have been made to treat and prevent acute and chronic
infections caused by the hepatitis C virus (HCV). Current treatments are unable to protect …
infections caused by the hepatitis C virus (HCV). Current treatments are unable to protect …
An assessment of toll-like receptor 7 and 8 gene polymorphisms with susceptibility to HIV-1 infection, AIDS development and response to antiretroviral therapy
I Zaidane, A Ouladlahsen, R Bensghir, H Chihab… - Immunology …, 2020 - Elsevier
Toll-like receptors (TLRs) play an important role in activating the innate immune response,
inducing inflammation and initiating the adaptive immune response. In this study, we assess …
inducing inflammation and initiating the adaptive immune response. In this study, we assess …
Antiviral response induced by toll-like receptor (TLR) 7/TLR8 activation inhibits human immunodeficiency virus type 1 infection in cord blood macrophages
AJ Pietrobon, FSY Yoshikawa… - The Journal of …, 2022 - academic.oup.com
Vertical transmission is the main mechanism of human immunodeficiency virus type 1 (HIV-
1) infection in infants, who may develop high viremia and rapidly progress to AIDS. Innate …
1) infection in infants, who may develop high viremia and rapidly progress to AIDS. Innate …