MicroRNAs (miRNAs) are a group of endogenous non-coding RNAs that regulate gene
expression. Alteration in miRNA expression results in changes in the profile of genes …

Osteoporosis is a “skeletal disorder characterized by compromised bone strength
predisposing a person to an increased risk of fracture” which, in light of demographic …

The discovery of miRNAs in the mid-90s has changed the dogma of gene expression
regulation. Currently, miRNAs are the main theme of thousands of publications each year …

Fragility fractures are increasingly recognized as a complication of both type 1 and type 2
diabetes, with fracture risk that increases with disease duration and poor glycemic control …

MicroRNAs (miRNAs) are small single-stranded RNAs belonging to a class of non-coding
RNAs with an average length of 18–22 nucleotides. Although not able to encode any …

Bone mineral density (BMD) assessed by DXA is used to evaluate bone health. In children,
total body (TB) measurements are commonly used; in older individuals, BMD at the lumbar …

Long-term exposure to a diabetic environment leads to changes in bone metabolism and
impaired bone micro-architecture through a variety of mechanisms on molecular and …

Type 2 diabetes mellitus (T2DM) is characterised by chronic low-grade inflammation,
recently referred to as 'metaflammation', a relevant factor contributing to the development of …

Context: Established bone turnover markers do not reflect fracture risk in idiopathic male and
premenopausal osteoporosis and the role of microRNAs (miRNAs) in these patients is …

The assessment of bone quality and the prediction of fracture risk in idiopathic osteoporosis
(IOP) are complex prospects as bone mineral density (BMD) and bone turnover markers …