Drosophila olfaction: past, present and future

R Benton - Proceedings of the Royal Society B, 2022 - royalsocietypublishing.org
Among the many wonders of nature, the sense of smell of the fly Drosophila melanogaster
might seem, at first glance, of esoteric interest. Nevertheless, for over a century, the 'nose'of …

Reprogramming to recover youthful epigenetic information and restore vision

Y Lu, B Brommer, X Tian, A Krishnan, M Meer, C Wang… - Nature, 2020 - nature.com
Ageing is a degenerative process that leads to tissue dysfunction and death. A proposed
cause of ageing is the accumulation of epigenetic noise that disrupts gene expression …

Sustentacular cell enwrapment of olfactory receptor neuronal dendrites: an update

F Liang - Genes, 2020 - mdpi.com
The pseudostratified olfactory epithelium (OE) may histologically appear relatively simple,
but the cytological relations among its cell types, especially those between olfactory receptor …

A transcriptomic taxonomy of Drosophila circadian neurons around the clock

D Ma, D Przybylski, KC Abruzzi, M Schlichting, Q Li… - Elife, 2021 - elifesciences.org
Many different functions are regulated by circadian rhythms, including those orchestrated by
discrete clock neurons within animal brains. To comprehensively characterize and assign …

Single-cell transcriptomes of developing and adult olfactory receptor neurons in Drosophila

CN McLaughlin, M Brbić, Q Xie, T Li, F Horns… - Elife, 2021 - elifesciences.org
Recognition of environmental cues is essential for the survival of all organisms.
Transcriptional changes occur to enable the generation and function of the neural circuits …

Single‐cell RNA sequencing in Drosophila: Technologies and applications

H Li - Wiley Interdisciplinary Reviews: Developmental …, 2021 - Wiley Online Library
Single‐cell RNA sequencing (scRNA‐seq) has emerged as a powerful tool for investigating
cell states and functions at the single‐cell level. It has greatly revolutionized transcriptomic …

Non-canonical odor coding in the mosquito

MA Younger, M Herre, OV Goldman, TC Lu… - BioRxiv, 2020 - biorxiv.org
Female Aedes aegypti mosquitoes show strong innate attraction to humans. This
chemosensory behavior is critical to species survival because females require a blood-meal …

Single cell RNA-seq analysis reveals temporally-regulated and quiescence-regulated gene expression in Drosophila larval neuroblasts

N Dillon, B Cocanougher, C Sood, X Yuan, AB Kohn… - Neural …, 2022 - Springer
The mechanisms that generate neural diversity during development remains largely
unknown. Here, we use scRNA-seq methodology to discover new features of the Drosophila …

Chemoreceptor Co-Expression in Drosophila Olfactory Neurons

D Task, CC Lin, A Vulpe, A Afify, S Ballou, M Brbić… - BioRxiv, 2020 - biorxiv.org
Drosophila melanogaster olfactory neurons have long been thought to express only one
chemosensory receptor gene family. There are two main olfactory receptor gene families in …

Neural connectivity molecules best identify the heterogeneous clock and dopaminergic cell types in the Drosophila adult brain

D Ma, N Herndon, JQ Le, KC Abruzzi, K Zinn… - Science …, 2023 - science.org
Our recent single-cell sequencing of most adult Drosophila circadian neurons indicated
notable and unexpected heterogeneity. To address whether other populations are similar …