Medicinal plants and natural compounds against acyclovir-resistant HSV infections
Herpes simplex virus (HSV), an alphaherpesvirus, is highly prevalent in the human
population and is known to cause oral and genital herpes and various complications …
population and is known to cause oral and genital herpes and various complications …
Synthesis of ursolic acid arylidene-hydrazide hybrid compounds and investigation of their cytotoxic and antimicrobial effects
H Şenol, RB Şahin, B Mercümek… - Natural Product …, 2023 - Taylor & Francis
In this study, 13 new hybrid compounds (7a-m) were synthesised starting from ursolic acid,
and their cytotoxic activities were investigated on the BEAS-2B and A549 cell lines. In …
and their cytotoxic activities were investigated on the BEAS-2B and A549 cell lines. In …
Oleanolic acid and its analogues: promising therapeutics for kidney disease
D Pan, Y Qu, C Shi, C Xu, J Zhang, H Du, X Chen - Chinese Medicine, 2024 - Springer
Kidney diseases pose a significant threat to human health due to their high prevalence and
mortality rates. Worryingly, the clinical use of drugs for kidney diseases is associated with …
mortality rates. Worryingly, the clinical use of drugs for kidney diseases is associated with …
Potential bioactive compounds and mechanisms of Fibraurea recisa Pierre for the treatment of Alzheimer's disease analyzed by network pharmacology and …
S Wang, Y Ma, Y Huang, Y Hu, Y Huang… - Frontiers in Aging …, 2022 - frontiersin.org
Introduction Heat-clearing and detoxifying Chinese medicines have been documented to
have anti-Alzheimer's disease (AD) activities according to the accumulated clinical …
have anti-Alzheimer's disease (AD) activities according to the accumulated clinical …
Zhi Zi Chi decoction (Gardeniae fructus and semen Sojae Praeparatum) attenuates anxious depression via modulating microbiota–gut–brain axis in corticosterone …
X Tian, G Wang, F Teng, X Xue, J Pan… - CNS Neuroscience …, 2024 - Wiley Online Library
Background The microbiota–gut–brain axis plays a critical role in neuropsychiatric
disorders, particularly anxious depression, and attracts more attention gradually. Zhi Zi Chi …
disorders, particularly anxious depression, and attracts more attention gradually. Zhi Zi Chi …
Delivery of Oleanolic Acid with Improved Antifibrosis Efficacy by a Cell Penetrating Peptide P10
L Wang, J Geng, H Wang - ACS Pharmacology & Translational …, 2023 - ACS Publications
Oleanolic acid (OA), a common pentacyclic triterpenoid found in plants, has several
therapeutic uses, including the treatment of hepatopathy disorders. However, due to OA's …
therapeutic uses, including the treatment of hepatopathy disorders. However, due to OA's …
The in vitro and in vivo study of oleanolic acid indole derivatives as novel anti-inflammatory agents: Synthesis, biological evaluation, and mechanistic analysis
J Jin, H He, X Zhang, R Wu, L Gan, D Li, Y Lu, P Wu… - Bioorganic …, 2021 - Elsevier
Oleanolic acid (OA) is a well-known natural product possessing many important
pharmacological activities; however, its weak bioactivities significantly restrict the potential …
pharmacological activities; however, its weak bioactivities significantly restrict the potential …
[HTML][HTML] Beneficial effects of oleanolic acid on hepatopancreas oxidative stress and intestinal microbiota structure of red swamp crayfish (Procambarus clarkia)
G Fu, J Wang, M Cai, J Zhang, H Hu, C Dai, X Zheng… - Aquaculture …, 2023 - Elsevier
This study aimed to evaluate the beneficial effects of oleanolic acid (OA) in the culture of red
swamp crayfish (Procambarus clarkia) by investigating the impact of dietary OA on growth …
swamp crayfish (Procambarus clarkia) by investigating the impact of dietary OA on growth …
Oleanolic Acid Inhibits SCD1 Gene Expression to Ameliorate Fructose‐Induced Hepatosteatosis through SREBP1c‐Dependent and‐Independent Mechanisms
L Yao, M Wang, J Zhang, X Luo, C Yuan… - Molecular Nutrition & …, 2023 - Wiley Online Library
Scope The mechanisms of oleanolic acid (OA) regulating hepatic sterol regulatory element‐
binding protein (SREBP) 1c/stearoyl‐CoA desaturase (SCD) 1 pathway to ameliorate …
binding protein (SREBP) 1c/stearoyl‐CoA desaturase (SCD) 1 pathway to ameliorate …
Mini-encyclopedia of mitochondria-relevant nutraceuticals protecting health in primary and secondary care—clinically relevant 3PM innovation
O Golubnitschaja, A Kapinova, N Sargheini, B Bojkova… - EPMA Journal, 2024 - Springer
Despite their subordination in humans, to a great extent, mitochondria maintain their
independent status but tightly cooperate with the “host” on protecting the joint life quality and …
independent status but tightly cooperate with the “host” on protecting the joint life quality and …