Abstract 21st century learning refers to students for 4C (Critical Thinking, Communication,
Collaboration, and Creativity) namely skills that students must have, such as problem …

Cancer stem cells (CSCs) as a small subpopulation in tumor bulk are believed to initiate
tumor formation and are responsible for the resistance to cancer therapy. The proliferation …

Cancer stem cells (CSCs) are an important cause of tumor recurrence and drug resistance.
As a new type of cell death that relies on iron ions and is strictly regulated by intracellular …

Epithelial growth factor receptor (EGFR) is a cell surface transmembrane receptor that
mediates the tyrosine signaling pathway to carry the extracellular messages inside the cell …

JAK/STAT signaling pathway is one of the important regulatory signaling cascades for the
myriad of cellular processes initiated by various types of ligands such as growth factors …

Tight junctions (TJs) are intercellular protein complexes that preserve tissue homeostasis
and integrity through the control of paracellular permeability and cell polarity. Recent …

Simple Summary Cancer is one of the most debated problems all over the world. Cancer
stem cells are considered responsible of tumor initiation, metastasis, drug resistance, and …

The safe and effective delivery of anticancer agents to diseased tissues is one of the
significant challenges in cancer therapy. Conventional anticancer agents are generally …

Colorectal cancer (CRC) represents the third most commonly diagnosed cancer and the
second leading cause of cancer death worldwide. The modern concept of cancer biology …

Malignant stem cells have long been considered a key therapeutic target in leukemia.
Therapeutic strategies designed to target the fundamental biology of leukemia stem cells …