[HTML][HTML] Good practices for 68Ga radiopharmaceutical production

BJB Nelson, JD Andersson, F Wuest… - EJNMMI …, 2022 - Springer
Abstract Background The radiometal gallium-68 (68Ga) is increasingly used in diagnostic
positron emission tomography (PET), with 68Ga-labeled radiopharmaceuticals developed …

Nanobodies in cancer

ER Verhaar, AW Woodham, HL Ploegh - Seminars in immunology, 2021 - Elsevier
For treatment and diagnosis of cancer, antibodies have proven their value and now serve as
a first line of therapy for certain cancers. A unique class of antibody fragments called …

The elements of life and medicines

P Chellan, PJ Sadler - Philosophical Transactions of the …, 2015 - royalsocietypublishing.org
Which elements are essential for human life? Here we make an element-by-element journey
through the periodic table and attempt to assess whether elements are essential or not, and …

Peptide-Based 68Ga-PET Radiotracer for Imaging PD-L1 Expression in Cancer

RA De Silva, D Kumar, A Lisok… - Molecular …, 2018 - ACS Publications
Tumors create and maintain an immunosuppressive microenvironment that promotes cancer
cell escape from immune surveillance. The immune checkpoint protein programmed death …

Biodistribution and first clinical results of 18F-SiFAlin-TATE PET: a novel 18F-labeled somatostatin analog for imaging of neuroendocrine tumors

H Ilhan, S Lindner, A Todica, CC Cyran, R Tiling… - European journal of …, 2020 - Springer
Abstract Introduction PET/CT using 68 Ga-labeled somatostatin analogs (SSA) targeting
somatostatin receptors (SSR) on the cell surface of well-differentiated neuroendocrine …

Type I collagen–targeted PET probe for pulmonary fibrosis detection and staging in preclinical models

P Désogère, LF Tapias, LP Hariri, NJ Rotile… - Science translational …, 2017 - science.org
Pulmonary fibrosis is scarring of the lungs that can arise from radiation injury, drug toxicity,
environmental or genetic causes, and for unknown reasons [idiopathic pulmonary fibrosis …

A nuclear chocolate box: the periodic table of nuclear medicine

PJ Blower - Dalton Transactions, 2015 - pubs.rsc.org
Radioisotopes of elements from all parts of the periodic table find both clinical and research
applications in radionuclide molecular imaging and therapy (nuclear medicine). This article …

Biological properties of metal complexes of curcumin

A Shakeri, Y Panahi, TP Johnston, A Sahebkar - BioFactors, 2019 - Wiley Online Library
Curcumin, a naturally occurring phenolic compound isolated from Curcuma longa, has
different pharmacological effects, including antiinflammatory, antimicrobial, antioxidant, and …

[HTML][HTML] Effect of morphology and (Sn, Cr) doping on in vitro antiproliferation properties of hydrothermally synthesized 1D GaOOH nanostructures

R Pilliadugula, J Haribabu, MKM Subarkhan… - Journal of science …, 2021 - Elsevier
GaOOH powders of submicron dimensions were synthesized through a simple, surfactant-
free hydrothermal synthesis at pH values of 7 and 14. Sn and Cr at concentrations of 2 mol …

Bifunctional gallium-68 chelators: Past, present, and future

P Spang, C Herrmann, F Roesch - Seminars in nuclear medicine, 2016 - Elsevier
This article reviews the development of bifunctional chelates for synthesising 68 Ga
radiopharmaceuticals. It structures the chelates into groups of macrocycles …