Abstract The programmed death-1 (PD-1) receptor is an immunosuppressive receptor
expressed on activated T-cells that elicits an inhibitory signal upon the engagement of its …

Cancer has a high incidence and mortality rate worldwide, which continues to grow as
millions of people are diagnosed annually. Metastatic disease caused by cancer is largely …

Since its first introduction some 20 years ago,[68Ga]-radiolabelled somatostatin receptor
agonists (SSAs) have gained high importance in the management of neuroendocrine …

We have recently introduced a 1, 4, 7-triazacyclononane (TACN) based chelating system
with additional five-membered azaheterocyclic substituents for complexation of radioactive …

NEMA characterization of PET systems is generally based on 18F because it is the most
relevant radioisotope for the clinical use of PET. 18F has a half-life of 109.7 min and decays …

Simple Summary In the present work we investigated the clinical utility of Al [18F] F-NOTA-
Octreotide (Al [18F] F-OC) in comparison to [68Ga] Ga-DOTA-TATE in patients diagnosed …

The αvβ3 integrin receptors have high expression on proliferating growing tumor cells of
different origins including non‐small‐cell lung cancer. RGD‐containing peptides target the …

A general protocol for the preparation of 18F-labeled AAAs and α-methyl-AAAs applying
alcohol-enhanced Cu-mediated radiofluorination of Bpin-substituted chiral complexes using …

The synthesis of two new hexadentate potentially tetra-anionic acyclic chelators, an N2O4-
donor bis (semicarbazone)(H4bsc) and an N2O2S2-donor bis (thiosemicarbazone)(H4btsc) …

Abstract Purpose Evaluation of [68 Ga] NODAGA-duramycin as a positron emission
tomography (PET) tracer of cell death for whole-body detection of chemotherapy-induced …