Computational studies of gene regulatory networks: in numero molecular biology

J Hasty, D McMillen, F Isaacs, JJ Collins - Nature Reviews Genetics, 2001 - nature.com
Remarkable progress in genomic research is leading to a complete map of the building
blocks of biology. Knowledge of this map is, in turn, setting the stage for a fundamental …

Cross signaling, cell specificity, and physiology

JE Dumont, S Dremier, I Pirson… - American Journal of …, 2002 - journals.physiology.org
The literature on intracellular signal transduction presents a confusing picture: every
regulatory factor appears to be regulated by all signal transduction cascades and to regulate …

MGS: a rule-based programming language for complex objects and collections

JL Giavitto, O Michel - Electronic Notes in Theoretical Computer Science, 2001 - Elsevier
We present the first results in the development of a new declarative programming language
called MGS. This language is devoted to the simulation of biological processes, especially …

[图书][B] Morphogenesis: origins of patterns and shapes

P Bourgine, A Lesne - 2010 - books.google.com
What are the relations between the shape of a system of cities and that of fish school? Which
events should happen in a cell in order that it participates to one of the finger of our hands …

Modeling the topological organization of cellular processes

JL Giavitto, O Michel - BioSystems, 2003 - Elsevier
The cell as a dynamical system presents the characteristics of having a dynamical structure.
That is, the exact phase space of the system cannot be fixed before the evolution and …

The topological structures of membrane computing

JL Giavitto, O Michel - Fundamenta Informaticae, 2002 - content.iospress.com
In its initial presentation, the P system formalism describes the topology of the membranes
as a set of nested regions. In this paper, we present an algebraic structure developped in …

Topological collections, transformations and their application to the modeling and the simulation of dynamical systems

JL Giavitto - International Conference on Rewriting Techniques and …, 2003 - Springer
I take the opportunity given by this invited talk to promote two ideas:(1) a topological point of
view can fertilize the notion of rewriting and (2) this topological approach of rewriting is at the …

Cellulat: an agent-based intracellular signalling model

PP González, M Cárdenas, D Camacho, A Franyuti… - Biosystems, 2003 - Elsevier
The theory of behaviour-based systems (or autonomous agents) constitutes a useful
approach for the modelling of intracellular signalling networks. In this sense, a cell can be …

[PDF][PDF] Computational models for integrative and developmental biology

JL Giavitto, C Godin, O Michel… - Univerite d'Evry, LaMI …, 2002 - spatial-computing.org
LaMI Computational Models for Integrative and Developmental Biology Page 1 LaMI Laboratoire
de Méthodes Informatiques Computational Models for Integrative and Developmental Biology …

Category theory and higher dimensional algebra: potential descriptive tools in neuroscience

R Brown, T Porter - arXiv preprint math/0306223, 2003 - arxiv.org
arXiv:math/0306223v2 [math.CT] 10 Feb 2008 Page 1 arXiv:math/0306223v2 [math.CT] 10 Feb
2008 Category Theory and Higher Dimensional Algebra: potential descriptive tools in …