Method and apparatus for quantitative and depth resolved hyperspectral fluorescence and reflectance imaging for surgical guidance

P Valdes, F Leblond, KD Paulsen, BC Wilson… - US Patent …, 2024 - Google Patents
An imaging system, such as a surgical microscope, laparoscope, or endoscope or integrated
with these devices, includes an illuminator providing patterned white light and/or fluorescent …

Driving light emissions according to a jitter specification in a multispectral, fluorescence, and laser mapping imaging system

JD Talbert, DM Wichern - US Patent 11,940,615, 2024 - Google Patents
Driving an emitter to emit pulses of electromagnetic radiation according to a jitter
specification in a hyperspectral, fluorescence, and laser mapping imaging system is …

Method and apparatus for medical imaging using differencing of multiple fluorophores

K Tichauer, RW Holt, F Leblond, P Valdes… - US Patent …, 2024 - Google Patents
A method of generating corrected fluorescence data of concentrations of a targeted
fluorophore in tissue of a subject includes administering first and second fluorescent contrast …

Systems and methods for virtual index-matching of diffusive media

JR Lorenzo, WI Yared, J Kempner - US Patent 9,901,254, 2018 - Google Patents
The invention relates to systems and methods for tomographic imaging of a subject
comprising diffuse media by converting measurements of electromagnetic radiation, eg …

Offset illumination of a scene using multiple emitters in a hyperspectral imaging system

JD Talbert, DM Wichern - US Patent 11,931,009, 2024 - Google Patents
Offset illumination using multiple emitters in a hyperspectral imaging system is described. A
system includes an emitter for emitting pulses of electromagnetic radiation and an image …

Driving light emissions according to a jitter specification in a spectral imaging system

JD Talbert, DM Wichern - US Patent 12,007,550, 2024 - Google Patents
Driving an emitter to emit pulses of electromagnetic radiation according to a jitter
specification in a hyperspectral imaging system is described. A system includes an emitter …

Driving light emissions according to a jitter specification in a fluorescence imaging system

JD Talbert, DM Wichern - US Patent 11,083,366, 2021 - Google Patents
Driving an emitter to emit pulses of electromagnetic radiation according to a jitter
specification in a fluorescence imaging system is described. A system includes an emitter for …

Systems and methods for rapid wide field illumination scanning for in vivo small animal fluorescence tomographic imaging

W Hurley, A Behrooz, M Meltzer, A Wilson - US Patent 11,141,064, 2021 - Google Patents
Presented herein are systems and methods for tomographic imaging that provide for rapid
illumination of multiple excitation locations across a large field of view by one or more …

Method and apparatus for medical imaging using differencing of multiple fluorophores

K Tichauer, RW Holt, F Leblond, P Valdes… - US Patent …, 2023 - Google Patents
(57) ABSTRACT A method of generating corrected fluorescence data of concentrations of a
targeted fluorophore in tissue of a subject includes administering first and second …

Optical imaging system

K Hassler, M Bucher - US Patent 9,255,882, 2016 - Google Patents
The invention relates to an optical imaging system (20) com prising an illumination unit (23),
a detection unit (24) and a measurement chamber (21) for receiving a subject to be …