Diabetes mellitus (DM) is a metabolic disorder, which if not managed properly, can lead to
serious health problems over time and impose significant financial burden on the patient …

In the last decade, cholesterol level has been implicated in several types of cancer,
including breast cancer. In the current study, we aimed to investigate the condition of lipid …

Exosomes are well established effectors of cell–cell communication. Their role on
maturation of embryonic cells located in hippocampus, seat of memory, is unknown. Here …

The paper reviews some of the mechanisms implicated in hepatotoxicity, which is induced
by an excess of lipids. The paper spans a wide variety of topics: from the molecular …

The tumor microenvironment is reprogrammed by cancer cells and participates in all stages
of tumor progression. Neutral ceramidase is a key regulator of ceramide, the central …

To promote the potential of arachidonic acid (ARA) for cancer prevention and management,
experiments were implemented to disclose the mechanisms of its tumoricidal action …

Background Clear cell renal cell carcinoma (ccRCC) is closely associated with steroid
hormones and their receptors affected by lipid metabolism. Recently, there has been …

The role of sphingomyelin metabolism and vitamin C in cancer has been widely described
with conflicting results ranging from a total absence of effect to possible preventive and/or …

Radiation therapy, particularly X-ray-based treatment, is widely used against cancer due to
its ability to induce cell death, hence local tumour control Recently, increasing attention has …

Sphingolipids are a diverse family of complex lipids typically composed of a sphingoid base
bound to a fatty acid via amide bond. The metabolism of sphingolipids has long remained …