Biofilm dispersion
KP Rumbaugh, K Sauer - Nature Reviews Microbiology, 2020 - nature.com
The formation of microbial biofilms enables single planktonic cells to assume a multicellular
mode of growth. During dispersion, the final step of the biofilm life cycle, single cells egress …
mode of growth. During dispersion, the final step of the biofilm life cycle, single cells egress …
Poloxamer: A versatile tri-block copolymer for biomedical applications
Poloxamers, also called Pluronic, belong to a unique class of synthetic tri-block copolymers
containing central hydrophobic chains of poly (propylene oxide) sandwiched between two …
containing central hydrophobic chains of poly (propylene oxide) sandwiched between two …
Antimicrobial peptides and their therapeutic potential for bacterial skin infections and wounds
A Pfalzgraff, K Brandenburg, G Weindl - Frontiers in pharmacology, 2018 - frontiersin.org
Alarming data about increasing resistance to conventional antibiotics are reported, while at
the same time the development of new antibiotics is stagnating. Skin and soft tissue …
the same time the development of new antibiotics is stagnating. Skin and soft tissue …
Healthcare-associated infections, medical devices and biofilms: risk, tolerance and control
SL Percival, L Suleman, C Vuotto… - Journal of medical …, 2015 - microbiologyresearch.org
Biofilms are of great importance in infection control and healthcare-associated infections
owing to their inherent tolerance and 'resistance'to antimicrobial therapies. Biofilms have …
owing to their inherent tolerance and 'resistance'to antimicrobial therapies. Biofilms have …
Antifouling and antimicrobial biomaterials: an overview
The use of implantable medical devices is a common and indispensable part of medical
care for both diagnostic and therapeutic purposes. However, as side effect, the implant of …
care for both diagnostic and therapeutic purposes. However, as side effect, the implant of …
Approaches to dispersing medical biofilms
D Fleming, KP Rumbaugh - Microorganisms, 2017 - mdpi.com
Biofilm-associated infections pose a complex problem to the medical community, in that
residence within the protection of a biofilm affords pathogens greatly increased tolerances to …
residence within the protection of a biofilm affords pathogens greatly increased tolerances to …
Biofilms in diabetic foot ulcers: impact, risk factors and control strategies
Diabetic foot ulcers (DFUs) are a serious complication from diabetes mellitus, with a huge
economic, social and psychological impact on the patients' life. One of the main reasons why …
economic, social and psychological impact on the patients' life. One of the main reasons why …
Targeting biofilms therapy: current research strategies and development hurdles
Y Jiang, M Geng, L Bai - Microorganisms, 2020 - mdpi.com
Biofilms are aggregate of microorganisms in which cells are frequently embedded within a
self-produced matrix of extracellular polymeric substance (EPS) and adhere to each other …
self-produced matrix of extracellular polymeric substance (EPS) and adhere to each other …
Current therapeutic strategies in diabetic foot ulcers
A Perez-Favila, ML Martinez-Fierro… - Medicina, 2019 - mdpi.com
Diabetic foot ulcers (DFUs) are the fastest growing chronic complication of diabetes mellitus,
with more than 400 million people diagnosed globally, and the condition is responsible for …
with more than 400 million people diagnosed globally, and the condition is responsible for …
Exopolysaccharide biosynthetic glycoside hydrolases can be utilized to disrupt and prevent Pseudomonas aeruginosa biofilms
Bacterial biofilms present a significant medical challenge because they are recalcitrant to
current therapeutic regimes. A key component of biofilm formation in the opportunistic …
current therapeutic regimes. A key component of biofilm formation in the opportunistic …