Enzymatic dispersion of biofilms: An emerging biocatalytic avenue to combat biofilm-mediated microbial infections
Drug resistance by pathogenic microbes has emerged as a matter of great concern to
mankind. Microorganisms such as bacteria and fungi employ multiple defense mechanisms …
mankind. Microorganisms such as bacteria and fungi employ multiple defense mechanisms …
Small-molecule inhibition of bacterial biofilm
A Ghosh, N Jayaraman, D Chatterji - ACS omega, 2020 - ACS Publications
Antibiotic resistance is a massive and serious threat to human welfare and healthcare. Apart
from being genetically resistant to antibiotics, the other important mechanism by which …
from being genetically resistant to antibiotics, the other important mechanism by which …
Pseudomonas aeruginosa Biofilm Formation and Its Control
Microbes are hardly seen as planktonic species and are most commonly found as biofilm
communities in cases of chronic infections. Biofilms are regarded as a biological condition …
communities in cases of chronic infections. Biofilms are regarded as a biological condition …
Advanced strategies for combating bacterial biofilms
Biofilms are communities of microorganisms that are formed on and attached to living or
nonliving surfaces and are surrounded by an extracellular polymeric material. Biofilm …
nonliving surfaces and are surrounded by an extracellular polymeric material. Biofilm …
Biofilms: microbial shelters against antibiotics
S Hathroubi, MA Mekni, P Domenico… - Microbial Drug …, 2017 - liebertpub.com
Biofilms are communities of aggregated bacterial cells embedded in a self-produced
extracellular polymeric matrix. Biofilms are recalcitrant to antibiotic treatment and immune …
extracellular polymeric matrix. Biofilms are recalcitrant to antibiotic treatment and immune …
Enhancing the therapeutic use of biofilm-dispersing enzymes with smart drug delivery systems
Biofilm-dispersing enzymes degrade the extracellular polymeric matrix surrounding bacterial
biofilms, disperse the microbial community and increase their susceptibility to antibiotics and …
biofilms, disperse the microbial community and increase their susceptibility to antibiotics and …
In diabetic foot infections antibiotics are to treat infection, not to heal wounds
Introduction: Diabetic foot ulcers, especially when they become infected, are a leading
cause of morbidity and may lead to severe consequences, such as amputation. Optimal …
cause of morbidity and may lead to severe consequences, such as amputation. Optimal …
Approaches to targeting bacterial biofilms in cystic fibrosis airways
I Martin, V Waters, H Grasemann - International Journal of Molecular …, 2021 - mdpi.com
The treatment of lung infection in the context of cystic fibrosis (CF) is limited by a biofilm
mode of growth of pathogenic organisms. When compared to planktonically grown bacteria …
mode of growth of pathogenic organisms. When compared to planktonically grown bacteria …
Novel formulations for antimicrobial peptides
AM Carmona-Ribeiro, LDM Carrasco - International journal of molecular …, 2014 - mdpi.com
Peptides in general hold much promise as a major ingredient in novel supramolecular
assemblies. They may become essential in vaccine design, antimicrobial chemotherapy …
assemblies. They may become essential in vaccine design, antimicrobial chemotherapy …
[HTML][HTML] Bioactive antimicrobial peptides as therapeutic agents for infected diabetic foot ulcers
J Da Silva, EC Leal, E Carvalho - Biomolecules, 2021 - mdpi.com
Diabetic foot ulcer (DFU) is a devastating complication, affecting around 15% of diabetic
patients and representing a leading cause of non-traumatic amputations. Notably, the risk of …
patients and representing a leading cause of non-traumatic amputations. Notably, the risk of …