Micro‐organism resistance is an important challenge in modern medicine due to the global
uncontrolled use of antibiotics. Natural and synthetic antimicrobial peptides (AMP s) …

Microbial cells show a strong natural tendency to adhere to surfaces and to colonize them by
forming complex communities called biofilms. In this growth mode, biofilm-forming cells …

Background Anticaries agents must interfere with the adhesion of Streptococcus mutans and
its proliferation in dental biofilm, without causing host toxicity and bacterial resistance …

Abstract Treatment of non-healing wounds represents hitherto a severe dilemma because of
their failure to heal caused by repeated tissue insults, bacteria contamination and altered …

Biofilms play a major role in Staphylococcus aureus pathogenicity but respond poorly to
antibiotics. Here, we show that the antifungal caspofungin improves the activity of …

Bacterial antibiotic resistance has increased in recent decades, raising concerns in hospital
and community settings. Novel, innovative strategies are needed to eradicate bacteria …

A multistep strategy was used to generate a combined antibiofilm treatment that could
efficiently decrease the biomass of dense biofilms (≥ 6× 10 7 CFU/cm 2). Several …

Wound management is an important and increasing global issue. Infection of a wound can
cause a delay in wound healing and pain, but also more serious complications like tissue …

Background Pseudomonas aeruginosa is a nosocomial pathogen that causes severe
infections in immunocompromised patients. Biofilm plays a significant role in the resistance …

Objectives To investigate the mechanism of action at the molecular level of pepR, a
multifunctional peptide derived from the Dengue virus capsid protein, against …