Direct oral anticoagulant use: a practical guide to common clinical challenges

A Chen, E Stecker, B A. Warden - Journal of the American Heart …, 2020 - Am Heart Assoc
Direct oral anticoagulants (DOAC s) have quickly become attractive alternatives to the long‐
standing standard of care in anticoagulation, vitamin K antagonist. DOAC s are indicated for …

Risk and management of bleeding complications with direct oral anticoagulants in patients with atrial fibrillation and venous thromboembolism: a narrative review

S Ballestri, E Romagnoli, D Arioli, V Coluccio… - Advances in …, 2023 - Springer
Atrial fibrillation (AF) and venous thromboembolism (VTE) are highly prevalent conditions
with a significant healthcare burden, and represent the main indications for anticoagulation …

[HTML][HTML] Deep vein thrombosis

SM Waheed, P Kudaravalli, DT Hotwagner - 2018 - europepmc.org
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Effectiveness and safety of apixaban vs. warfarin in venous thromboembolism patients with obesity and morbid obesity

A Cohen, J Sah, T Lee, L Rosenblatt… - Journal of Clinical …, 2021 - mdpi.com
This study integrated 5 United States healthcare claims databases to evaluate the risk of
recurrent venous thromboembolism (VTE) and major bleeding (MB) among VTE patients …

Effectiveness and safety of oral anticoagulants among NVAF patients with obesity: insights from the ARISTOPHANES study

S Deitelzweig, A Keshishian, A Kang… - Journal of clinical …, 2020 - mdpi.com
This ARISTOPHANES analysis examined stroke/systemic embolism (SE) and major
bleeding (MB) among a subgroup of nonvalvular atrial fibrillation (NVAF) patients with …

Dosage of anticoagulants in obesity: recommendations based on a systematic review

A Abildgaard, SA Madsen… - Seminars in thrombosis …, 2020 - thieme-connect.com
Anticoagulants are frequently used as thromboprophylaxis and in patients with atrial
fibrillation (AF) or venous thromboembolism (VTE). While obesity rates are reaching …

Patients with higher body mass index treated with direct/novel oral anticoagulants (DOAC/NOAC) for atrial fibrillation experience worse clinical outcomes

M Lucijanic, I Jurin, H Jurin, T Lucijanic… - International journal of …, 2020 - Elsevier
Introduction Due to fixed dosing of direct oral anticoagulants (DOACs), uncertainty exists
about their efficacy in a population of obese/overweight patients. Patients and methods We …

Anti-factor Xa–based anticoagulation during extracorporeal membrane oxygenation: potential problems and possible solutions

M Ranucci, M Cotza, G Isgro, G Carboni… - … in thrombosis and …, 2020 - thieme-connect.com
Choices for monitoring of unfractionated heparin (UFH) anticoagulation in extracorporeal
membrane oxygenation (ECMO) patients include activated clotting time, activated partial …

Effectiveness and safety of Apixaban versus warfarin in obese patients with Nonvalvular atrial fibrillation enrolled in Medicare and veteran affairs

S Deitelzweig, J Sah, A Kang, C Russ, M Preib… - The American Journal of …, 2022 - Elsevier
Real-world studies have evaluated the use of anticoagulants in obese patients with
nonvalvular atrial fibrillation (NVAF), but they have been limited by sample size or the use of …

[PDF][PDF] Body weight is negatively associated with direct oral anticoagulant trough concentrations in dabigatran and apixaban users

JM Borst, N van Rein, ECMD Bakker… - British Journal of …, 2020 - repub.eur.nl
Direct oral anticoagulants (DOACs, ie dabigatran, apixaban, edoxaban and rivaroxaban) are
prescribed in fixed-dose regimens to treat and prevent thrombosis. 1 The market …