Anti-inflammatory potential of ulvan

N Flórez-Fernández, A Rodríguez-Coello… - International Journal of …, 2023 - Elsevier
Green seaweeds are a widespread group of marine macroalgae that could be regarded as
biorenewable source of valuable compounds, in particular sulfated polysaccharides like …

[HTML][HTML] Carbon dioxide and MAPK signalling: towards therapy for inflammation

H Gałgańska, W Jarmuszkiewicz… - Cell Communication and …, 2023 - Springer
Inflammation, although necessary to fight infections, becomes a threat when it exceeds the
capability of the immune system to control it. In addition, inflammation is a cause and/or …

Chlorpyrifos induces placental oxidative stress and barrier dysfunction by inducing mitochondrial apoptosis through the ERK/MAPK signaling pathway: in vitro and in …

J Bai, S Deng, H Fu, Q Yang, F Ren, S Zeng… - Science of The Total …, 2023 - Elsevier
Chlorpyrifos (CPF) is an organophosphorus pesticide that is widely used in agricultural
production and residential environments worldwide. In this study, we determined the harmful …

[HTML][HTML] Dabrafenib protects from cisplatin-induced hearing loss in a clinically relevant mouse model

MA Ingersoll, RD Lutze, CK Pushpan, RG Kelmann… - JCI insight, 2023 - ncbi.nlm.nih.gov
The widely used chemotherapy cisplatin causes permanent hearing loss in 40%–60% of
patients with cancer. One drug, sodium thiosulfate, is approved by the FDA for use in …

[HTML][HTML] The potential of glucose treatment to reduce reactive oxygen species production and apoptosis of inflamed neural cells in vitro

JH Cherng, SJ Chang, HD Tsai, CF Chun, GY Fan… - Biomedicines, 2023 - mdpi.com
Neuroinflammation is a key feature in the pathogenesis of entrapment neuropathies. Clinical
trial evidence suggests that perineural injection of glucose in water at entrapment sites has …

Pleiotropic effects of BAFF on the senescence-associated secretome and growth arrest

M Rossi, C Anerillas, ML Idda, R Munk, CH Shin… - Elife, 2023 - elifesciences.org
Senescent cells release a variety of cytokines, proteases, and growth factors collectively
known as the senescence-associated secretory phenotype (SASP). Sustained SASP …

Tetrahedral-framework nucleic acid loaded with MicroRNA-155 enhances immunocompetence in cyclophosphamide-induced immunosuppressed mice by modulating …

X Qin, B Zhang, X Sun, M Zhang, D Xiao… - … Applied Materials & …, 2023 - ACS Publications
Nanomaterials are often used as immunomodulators because they can be tailored by a
controllable process. In this work, a complex based on a tetrahedral framework nucleic acid …

[HTML][HTML] Activin A induces apoptosis of human lung adenocarcinoma A549 cells through endoplasmic reticulum stress pathway

F Zhang, Y Qi, J Li, B Liu, Z Liu… - Oncology …, 2024 - spandidos-publications.com
Activin A, a member of the transforming growth factor‑β (TGF‑β) superfamily, has been
implicated in the tumorigenesis and progression of various cancers. However, it remains …

[HTML][HTML] Unleashing spinal cord repair: the role of cAMP-specific PDE inhibition in attenuating neuroinflammation and boosting regeneration after traumatic spinal cord …

F Mussen, JV Broeckhoven, N Hellings… - International Journal of …, 2023 - mdpi.com
Traumatic spinal cord injury (SCI) is characterized by severe neuroinflammation and
hampered neuroregeneration, which often leads to permanent neurological deficits. Current …

Pterostilbene as a therapeutic alternative for central nervous system disorders: A review of the current status and perspectives

X Qu, L Zhang, L Wang - Journal of Agricultural and Food …, 2023 - ACS Publications
Neurological disorders are diverse, have complex causes, and often result in disability; yet,
effective treatments remain scarce. The resveratrol derivative pterostilbene possesses …