Alzheimer's disease, the leading cause of dementia in the elderly, is a neurodegenerative
condition characterized by accumulation of amyloid plaques and neurofibrillary tangles in …

Alzheimer's disease (AD) is a complex, multi-factorial disease affecting various brain
systems. This complexity implies that successful therapies must be directed against several …

Alzheimer's disease (AD) is a type of incurable neurodegenerative disease that is
characterized by the accumulation of amyloid-β (Aβ; plaques) and tau hyperphosphorylation …

Chronic conditions such as obesity, diabetes, and dementia are increasing in the United
States (US) population. Knowledge of these chronic conditions, preventative measures, and …

Preventing the onset of dementia and Alzheimer's disease (AD), improving the diagnosis,
and slowing the progression of these diseases remain a challenge. The aim of this study …

Oxysterols are oxidized forms of cholesterol generated from cholesterol by auto‐oxidation,
enzymatic processes, or both. Some of them (7‐ketocholesterol, 7β‐hydroxycholesterol and …

In the middle of the coronavirus disease 19 (COVID-19) outbreak, the main efforts of the
scientific community are rightly all focused on identifying efficient pharmacological …

The Mediterranean diet is associated with health benefits due to bioactive compounds such
as polyphenols. The biological activities of three polyphenols (quercetin (QCT), resveratrol …

Introduction: Metformin is currently first line therapy for type 2 diabetes (T2D). The
mechanism of action of metformin involves activation of AMP-activated protein kinase …

Neurological disorders are ranked as the leading cause of disability and the second leading
cause of death worldwide, underscoring an urgent necessity to develop novel …