Sinus node dysfunction and atrial fibrillation—Relationships, clinical phenotypes, new mechanisms, and treatment approaches

S Duan, J Du - Ageing Research Reviews, 2023 - Elsevier
Although the anatomical basis of the pathogenesis of sinus node dysfunction (SND) and
atrial fibrillation (AF) is located primarily in the left and right atria, increasing evidence …

Arrhythmic Effects Evaluated on Caenorhabditis elegans: The Case of Polypyrrole Nanoparticles

SY Srinivasan, PA Illera, D Kukhtar… - ACS …, 2023 - ACS Publications
Experimental studies and clinical trials of nanoparticles for treating diseases are increasing
continuously. However, the reach to the market does not correlate with these efforts due to …

[HTML][HTML] Atrial structural remodeling and atrial fibrillation substrate: A histopathological perspective

T Yamaguchi - Journal of Cardiology, 2024 - Elsevier
Atrial fibrillation (AF) substrate progresses with the advancement of atrial structural
remodeling, resulting in AF perpetuation and recurrence. Although fibrosis is considered a …

[HTML][HTML] Discovery of GJC1 (Cx45) as a New Gene Underlying Congenital Heart Disease and Arrhythmias

YJ Li, J Wang, WG Ye, XY Liu, L Li, XB Qiu, H Chen… - Biology, 2023 - mdpi.com
Simple Summary Congenital heart disease is associated with substantial mortality and
morbidity as well as socioeconomic burden, and increasing research underscores the …

[HTML][HTML] Identification and validation of potential biomarkers for atrial fibrillation based on integrated bioinformatics analysis

F Tong, Z Sun - Frontiers in Cell and Developmental Biology, 2024 - frontiersin.org
Background: Globally, the most common form of arrhythmias is atrial fibrillation (AF), which
causes severe morbidity, mortality, and socioeconomic burden. The application of machine …

[HTML][HTML] Discovery of TBX20 as a Novel Gene Underlying Atrial Fibrillation

N Li, YJ Li, XJ Guo, SH Wu, WF Jiang, DL Zhang… - Biology, 2023 - mdpi.com
Simple Summary Atrial fibrillation (AF), the most prevalent sustained dysrhythmia, is
accountable for substantial mortality and morbidity. Accumulating convincing evidence …

Pinocembrin attenuates susceptibility to atrial fibrillation in rats with pulmonary arterial hypertension

Y Yi, Y Tianxin, L Zhangchi, Z Cui, W Weiguo… - European Journal of …, 2023 - Elsevier
Background Pulmonary arterial hypertension (PAH) is a disease characterized by
pulmonary vascular remodeling that triggers fibrosis and excessive myocardium apoptosis …

[HTML][HTML] Connexin hemichannels as candidate targets for cardioprotective and anti-arrhythmic treatments

L Leybaert, MAJ De Smet, A Lissoni… - The Journal of …, 2023 - Am Soc Clin Investig
Connexins are crucial cardiac proteins that form hemichannels and gap junctions. Gap
junctions are responsible for the propagation of electrical and chemical signals between …

[HTML][HTML] Tic-Tac: A Translational Approach in Mechanisms Associated with Irregular Heartbeat and Sinus Rhythm Restoration in Atrial Fibrillation Patients

A Parra-Lucares, E Villa, E Romero-Hernández… - International Journal of …, 2023 - mdpi.com
Atrial fibrillation (AF) is a prevalent cardiac condition predominantly affecting older adults,
characterized by irregular heartbeat rhythm. The condition often leads to significant disability …

心房颤动的发病机制及治疗进展.

李含, 蔡薇 - Journal of Practical Electrocardiology, 2024 - search.ebscohost.com
心房颤动(简称房颤) 是危害我国中老年人群健康的重要疾病, 与脑卒中, 死亡风险有关.
目前房颤的发生和发展可通过心房结构重构, 电重构, 炎症, 自主神经系统障碍, 非编码RNA …