Abstract In 1956, Riker Laboratories, Inc.,(now 3 M Drug Delivery Systems) introduced the
first pressurized metered dose inhaler (MDI). In many respects, the introduction of the MDI …

The pulmonary route of administration has proven to be effective in local and systemic
delivery of miscellaneous drugs and biopharmaceuticals to treat pulmonary and non …

Lactose is the most commonly used excipient in carrier-based dry powder inhalation (DPI)
formulations. Numerous inhalation therapies have been developed using lactose as a …

Pulmonary administration of drugs presents several advantages in the treatment of many
diseases. Considering local and systemic delivery, drug inhalation enables a rapid and …

Purpose Respiratory disorders pose a major threat to the morbidity and mortality to public
health. Here we reviewed the nanotechnology based pulmonary drug delivery using …

Background Inhaled medication is the cornerstone of the pharmacological treatment for
patients with asthma and chronic obstructive pulmonary disease (COPD). Several inhaler …

The lungs are an attractive route for non-invasive drug delivery with advantages for both
systemic and local applications. Incorporating therapeutics with polymeric nanoparticles …

A wide range of dry powder inhaler (DPI) devices are currently available on the market to
deliver drugs into lungs with a view to maximise drug delivery with low variability. DPIs also …

The delivery efficiency of dry-powder products for inhalation is dependent upon the drug
formulation, the inhaler device, and the inhalation technique. Dry powder formulations are …

Dry powder bronchodilator devices have an internal resistance. Effective use depends on
the patient generating an adequate inspiratory flow to break up the powder packets into …