Covering: up to 2010 This review focuses on recent developments in the use of natural
products as therapeutics for Alzheimer's disease. The compounds span a diverse array of …

Objectives The inhibition of acetylcholinesterase (AChE), the key enzyme in the breakdown
of acetylcholine, is currently the main pharmacological strategy available for Alzheimer's …

During the past decade, it has been reported that the consumption of certain foods and
spices such as pepper may have a positive effect on health. The present study evaluates the …

A series of around eight novel chalcone based coumarin derivatives (23a-h) was designed,
subjected to in-silico ADMET prediction, synthesized, characterized by IR, NMR, Mass …

Introduction: Stem cell-based regenerative medicine has provided an excellent opportunity
to investigate therapeutic strategies and innovative treatments for Alzheimer's disease (AD) …

Rationale Imperatorin, a naturally occurring furanocoumarin, inactivates gamma-
aminobutyric acid transaminase and inhibits acetylcholinesterase activity. Objectives The …

The first report in literature of the isolation of coumarin was in the year 1820. After this report,
other papers were published demonstrating the isolation and synthesis of coumarin and …

BACKGROUND: The replacement of synthetic antioxidants by safe natural antioxidants
fosters research on the screening of vegetables and food as sources of new antioxidants …

Dementia pathologies such as Alzheimer's disease (AD) are reaching epidemic proportions,
yet they are not successfully managed by effective symptomatic treatments. Only five drugs …

The essential oils of Origanum ehrenbergii and O. syriacum collected in Lebanon were
analysed by GC and GC–MS and evaluated for their anticholinesterase, NO production …