[HTML][HTML] Head and neck cancer management and cancer stem cells implication

OA Elkashty, R Ashry, SD Tran - The Saudi Dental Journal, 2019 - Elsevier
Head and neck squamous cell carcinomas (HNSCCs) arise in the mucosal linings of the
upper aerodigestive tract and are heterogeneous in nature. Risk factors for HNSCCs are …

Genomic insights into head and neck cancer

TN Beck, EA Golemis - Cancers of the head & neck, 2016 - Springer
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer
worldwide and is frequently impervious to curative treatment efforts. Similar to other cancers …

Inhibitors of the PD-1/PD-L1 axis for the treatment of head and neck cancer: current status and future perspectives

X Ran, K Yang - Drug design, development and therapy, 2017 - Taylor & Francis
Head and neck cancer (HNC) is a common malignant tumor, but traditional therapeutic
methods have unsatisfactory curative effects and many complications occur. Hence, there is …

Immune checkpoint inhibitors, small-molecule immunotherapies and the emerging role of neutrophil extracellular traps in therapeutic strategies for head and neck …

CH O'Meara, Z Jafri, LM Khachigian - International Journal of Molecular …, 2023 - mdpi.com
Immune checkpoint inhibitor (ICI) therapy has revolutionized the treatment of many cancer
types, including head and neck cancers (HNC). When checkpoint and partner proteins bind …

Precision therapy of head and neck squamous cell carcinoma

PJ Polverini, NJ D'silva, YL Lei - Journal of dental research, 2018 - journals.sagepub.com
Precision medicine is an approach to disease prevention and treatment that takes into
account genetic variability and environmental and lifestyle influences that are unique to …

Role of EGFR as a prognostic factor for survival in head and neck cancer: a meta-analysis

S Keren, Z Shoude, Z Lu, Y Beibei - Tumor Biology, 2014 - Springer
The prognostic role of epidermal growth factor receptor (EGFR) in head and neck squamous
cell carcinoma (HNSCC) remains controversial. The goal of this study was to summarize …

Targeting cellular and molecular drivers of head and neck squamous cell carcinoma: current options and emerging perspectives

S Ausoni, P Boscolo-Rizzo, B Singh… - Cancer and Metastasis …, 2016 - Springer
Despite improvements in functional outcomes attributable to advances in radiotherapy,
chemotherapy, surgical techniques, and imaging techniques, survival in head and neck …

Recent progress in therapeutic treatments and screening strategies for the prevention and treatment of HPV-associated head and neck cancer

SN Whang, M Filippova, P Duerksen-Hughes - Viruses, 2015 - mdpi.com
The rise in human papillomavirus (HPV)-associated head and neck squamous cell
carcinoma (HNSCC) has elicited significant interest in the role of high-risk HPV in …

[HTML][HTML] Nimotuzumab combined with concurrent chemoradiotherapy in locally advanced nasopharyngeal carcinoma: a retrospective analysis

Z Liu, Y Zhao, J Tang, Y Zhou, W Yang, Y Qiu… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Nimotuzumab is a blocking monoclonal antibody against epidermal growth factor receptor
(EGFR). However, little is known about the safety and preliminary efficacy of nimotuzumab …

Critical roles of EGFR family members in breast cancer and breast cancer stem cells: targets for therapy

LS Steelman, T Fitzgerald… - Current …, 2016 - ingentaconnect.com
The roles of the epidermal growth factor receptor (EGFR) signaling pathway in various
cancers including breast, bladder, brain, colorectal, esophageal, gastric, head and neck …