Nimotuzumab in combination with radiotherapy in high grade glioma patients: a single institution experience

MT Solomon, N Miranda, E Jorrín, I Chon… - Cancer biology & …, 2014 - Taylor & Francis
Nimotuzumab, a humanized antibody targeting epidermal growth factor receptor, has potent
anti-proliferative, anti-angiogenic, and pro-apoptotic effects in vitro and in vivo. It also …

Clinical application of genetics to guide prevention and treatment of oral diseases

KS Kornman, PJ Polverini - Clinical genetics, 2014 - Wiley Online Library
Dental care costs in the United States exceed $100 billion annually. Personalized medicine
efforts in dentistry are driven by potentially compelling clinical utility and cost‐effectiveness …

Osteopontin splice variants expression is involved on docetaxel resistance in PC3 prostate cancer cells

KDM Nakamura, TM Tilli, JL Wanderley, A Palumbo… - Tumor Biology, 2016 - Springer
Osteopontin (OPN) is a phosphoprotein that activates several aspects of tumor progression.
Alternative splicing of the OPN primary transcript generates three splicing isoforms, OPNa …

In Vitro and In Vivo Synergistic Antitumor Activity of the Combination of BKM120 and Erlotinib in Head and Neck Cancer: Mechanism of Apoptosis and Resistance

ASM Anisuzzaman, A Haque, D Wang… - Molecular cancer …, 2017 - AACR
We previously reported that the EGFR-targeted inhibitor erlotinib induces G1 arrest of
squamous cell carcinoma of the head and neck (SCCHN) cell lines without inducing …

Eating green: shining light on the use of dietary phytochemicals as a modern approach in the prevention and treatment of head and neck cancers

LL Eastham, CM Howard… - Current Topics in …, 2018 - ingentaconnect.com
Enthusiasm for the use of dietary bioactive compounds as chemopreventive agents and
adjuvants for current therapies has increased laboratory research conducted on several …

[HTML][HTML] Squamous cell carcinoma of the scrotum: A look beyond the chimneystacks

R Vyas, H Zargar, R Di Trolio… - World Journal of …, 2014 - ncbi.nlm.nih.gov
Despite the low incidence, squamous cell carcinoma (SCC) remains the most common
scrotal malignancy with a propensity for recurrence and metastasis. In recent years there …

EGFR, KRAS, BRAF, and PIK3CA characterization in squamous cell anal cancer

V Martin, E Zanellato, A Franzetti-Pellanda, F Molinari… - 2014 - digitum.um.es
Background: Combined chemoradiation therapy is the gold standard in the treatment of
squamous cell anal cancer (SCAC). However, even if the response rate is very high, many …

Response of head and neck squamous cell carcinoma cells carrying PIK3CA mutations to selected targeted therapies

ED Wirtz, D Hoshino, AT Maldonado… - … –Head & Neck …, 2015 - jamanetwork.com
Importance ThePIK3CAmutation is one of the most common mutations in head and neck
squamous cell carcinoma (HNSCC). Through this research we attempt to elicit the role of …

[HTML][HTML] Combining antiangiogenic therapy and radiation in nasopharyngeal carcinoma

Z Chen, XH Xu - Saudi Medical Journal, 2015 - ncbi.nlm.nih.gov
Radiation therapy is the primary treatment in nasopharyngeal carcinoma (NPC), and the
effect of radiation therapy is strongly related to the oxygen content of cancer cells. That …

Head and neck squamous cell carcinoma: Exploring frontiers of combinatorial approaches with tyrosine kinase inhibitors and immune checkpoint therapy

JF Scarini, L Lavareze, RA de Lima-Souza… - Critical Reviews in …, 2022 - Elsevier
Squamous cell carcinomas (SCC) are the most common malignant tumors that arise in the
head and neck. Despite advances in the management of affected patients, the mortality …