Head and neck squamous cell carcinoma: Exploring frontiers of combinatorial approaches with tyrosine kinase inhibitors and immune checkpoint therapy

JF Scarini, L Lavareze, RA de Lima-Souza… - Critical Reviews in …, 2022 - Elsevier
Squamous cell carcinomas (SCC) are the most common malignant tumors that arise in the
head and neck. Despite advances in the management of affected patients, the mortality …

[HTML][HTML] Treatment outcomes of 257 patients with locoregionally advanced nasopharyngeal carcinoma treated with nimotuzumab plus intensity-modulated …

F Wang, C Jiang, Z Ye, T Liu, Q Sun, F Yan, W Qin… - Translational …, 2018 - Elsevier
OBJECTIVES: To report the long-term outcome and toxicity of locoregionally advanced
nasopharyngeal carcinoma (LA NPC) treated with nimotuzumab (h-R3) plus intensity …

Predictive features and potential treatment targets for oral tongue cancer

A Elseragy - 2023 - oulurepo.oulu.fi
Oral tongue squamous cell carcinoma (OTSCC) stands as the most common malignancy in
the oral cavity. It is characterized by its aggressive course and has the worst prognosis of all …

Combining molecular targeted agents with radiation therapy for malignant gliomas

C Scaringi, RM Enrici, G Minniti - OncoTargets and therapy, 2013 - Taylor & Francis
The expansion in understanding the molecular biology that characterizes cancer cells has
led to the rapid development of new agents to target important molecular pathways …

Concurrent chemoradiotherapy combined with nimotuzumab in stage III–IVa nasopharyngeal carcinoma: a retrospective analysis

Z Cai, D Chen, W Qiu, C Liang, Y Huang… - Journal of Cancer …, 2023 - Springer
Purpose The efficacy and safety of nimotuzumab (NTZ) added to concurrent
chemoradiotherapy (CCRT) were investigated in patients with stage III–IVa nasopharyngeal …

[HTML][HTML] Toward the use of precision medicine for the treatment of head and neck squamous cell carcinoma

W Gong, Y Xiao, Z Wei, Y Yuan, M Qiu, C Sun, X Zeng… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Precision medicine is a new strategy that aims at preventing and treating human diseases
by focusing on individual variations in people's genes, environment and lifestyle. Precision …

Pneumatosis cystoides intestinalis after cetuximab chemotherapy for squamous cell carcinoma of parotid gland

C Petrides, N Kyriakos, I Andreas… - Case Reports in …, 2015 - Wiley Online Library
Pneumatosis intestinalis, defined as gas in the bowel wall, is often first identified on
abdominal radiographs or computed tomography (CT) scans. It is a radiographic finding and …

[HTML][HTML] Long-term use of nimotuzumab in combination with intensity-modulated radiotherapy and chemotherapy in the treatment of locoregionally advanced …

W Fangzheng, J Chuner, Y Zhiming, L Tongxin… - Oncology …, 2018 - ncbi.nlm.nih.gov
In this retrospective review of a single institution's experience, the efficacy and safety of the
long-term use of nimotuzumab in combination with intensity-modulated radiotherapy (IMRT) …

[HTML][HTML] Absent and abundant MET immunoreactivity is associated with poor prognosis of patients with oral and oropharyngeal squamous cell carcinoma

MJ De Herdt, SM Willems, B van der Steen, R Noorlag… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Although the receptor tyrosine kinase (RTK) MET is widely expressed in head and neck
squamous cell carcinoma (HNSCC), its prognostic value remains unclear. This might be due …

131I-Nimotuzumab–A potential radioimmunotherapeutic agent in treatment of tumors expressing EGFR

M Kameswaran, G Samuel, HD Sarma… - Applied Radiation and …, 2015 - Elsevier
The anti-EGFR antibody Nimotuzumab was radioiodinated with I-131 by Chloramine T and
Iodogen methods. The 131 I-Nimotuzumab was purified and characterized by HPLC …