[HTML][HTML] Modeling membranes in situ
CM Brown, SJ Marrink - Current Opinion in Structural Biology, 2024 - Elsevier
Molecular dynamics simulations of cellular membranes have come a long way—from simple
model lipid bilayers to multicomponent systems capturing the crowded and complex nature …
model lipid bilayers to multicomponent systems capturing the crowded and complex nature …
MTCH2 in Metabolic Diseases, Neurodegenerative Diseases, Cancers, Embryonic Development and Reproduction
X Peng, Y Yang, R Hou, L Zhang, C Shen… - Drug Design …, 2024 - Taylor & Francis
Abstract Mitochondrial carrier homolog 2 (MTCH2) is a member of the solute carrier 25
family, located on the outer mitochondrial membrane. MTCH2 was first identified in 2000 …
family, located on the outer mitochondrial membrane. MTCH2 was first identified in 2000 …
[HTML][HTML] Phospholipids are imported into mitochondria by VDAC, a dimeric beta barrel scramblase
H Jahn, L Bartoš, GI Dearden, JS Dittman… - Nature …, 2023 - nature.com
Mitochondria are double-membrane-bounded organelles that depend critically on
phospholipids supplied by the endoplasmic reticulum. These lipids must cross the outer …
phospholipids supplied by the endoplasmic reticulum. These lipids must cross the outer …
[HTML][HTML] MTCH2 cooperates with MFN2 and lysophosphatidic acid synthesis to sustain mitochondrial fusion
Fusion of the outer mitochondrial membrane (OMM) is regulated by mitofusin 1 (MFN1) and
2 (MFN2), yet the differential contribution of each of these proteins is less understood …
2 (MFN2), yet the differential contribution of each of these proteins is less understood …
[HTML][HTML] Lactose Permease Scrambles Phospholipids
L Wang, P Bütikofer - Biology, 2023 - mdpi.com
Simple Summary Scramblases are proteins that translocate phospholipids from one leaflet
of a membrane bilayer to the other. Our work identifies that a well-characterized protein from …
of a membrane bilayer to the other. Our work identifies that a well-characterized protein from …
A BID-MTCH2 love story: Energizing mitochondria until apoptosis do them part?
A Gross - Bioenergetics Communications, 2024 - bioenergetics-communications.org
Mitochondrial carrier homolog 2 (MTCH2) is currently one of the most enigmatic
mitochondrial proteins. MTCH2's ligand is the pro-apoptotic BID protein, and the love story …
mitochondrial proteins. MTCH2's ligand is the pro-apoptotic BID protein, and the love story …
[HTML][HTML] Optimizing properties of translocation-enhancing transmembrane proteins
L Bartoš, M Drabinová, R Vácha - Biophysical Journal, 2024 - cell.com
Cell membranes act as semi-permeable barriers, often restricting the entry of large or
hydrophilic molecules. Nonetheless, certain amphiphilic molecules, such as antimicrobial …
hydrophilic molecules. Nonetheless, certain amphiphilic molecules, such as antimicrobial …