Antimicrobial Resistance Expressed by Neisseria gonorrhoeae: A Major Global Public Health Problem in the 21st Century

M Unemo, CD Rio, WM Shafer - Emerging Infections 10, 2016 - Wiley Online Library
The sexually transmitted infection gonorrhea is a very old malady that can be traced to
ancient Chinese, Egyptian, Roman, and Greek literature as well as in the Old Testament of …

[HTML][HTML] Proteomics-driven antigen discovery for development of vaccines against gonorrhea

RA Zielke, IH Wierzbicki, BI Baarda, PR Gafken… - Molecular & Cellular …, 2016 - ASBMB
Expanding efforts to develop preventive gonorrhea vaccines is critical because of the dire
possibility of untreatable gonococcal infections. Reverse vaccinology, which includes …

[HTML][HTML] Proteomics, bioinformatics and structure-function antigen mining for gonorrhea vaccines

BI Baarda, FG Martinez, AE Sikora - Frontiers in Immunology, 2018 - frontiersin.org
Expanding efforts to develop preventive gonorrhea vaccines is critical because of the
serious health consequences combined with the prevalence and the dire possibility of …

[HTML][HTML] Quantitative Proteomics of the 2016 WHO Neisseria gonorrhoeae Reference Strains Surveys Vaccine Candidates and Antimicrobial Resistance Determinants …

FE El-Rami, RA Zielke, T Wi, AE Sikora… - Molecular & Cellular …, 2019 - ASBMB
The sexually transmitted disease gonorrhea (causative agent: Neisseria gonorrhoeae)
remains an urgent public health threat globally because of its reproductive health …

[HTML][HTML] Sexually transmitted infections: old foes on the rise

D Carmona-Gutierrez, K Kainz, F Madeo - Microbial cell, 2016 - ncbi.nlm.nih.gov
Sexually transmitted infections (STIs) are commonly spread via sexual contact. It is
estimated that one million STIs are acquired every day worldwide. Besides their impact on …

[HTML][HTML] Gonorrhea: historical outlook

PP Jose, V Vivekanandan, K Sobhanakumari - Journal of Skin and …, 2020 - jsstd.org
Gonorrhea is one of the oldest sexually transmitted infections (STIs) known to humankind.
There is some conflict of opinion regarding its exact origin, but according to the general …

Biochemical characterization and redesign of the coenzyme specificity of a novel monofunctional NAD+-dependent homoserine dehydrogenase from the human …

W Tang, X Dong, J Meng, Y Feng, M Xie, H Xu… - Protein Expression and …, 2021 - Elsevier
Gonorrhoea, caused by Neisseria gonorrhoeae, is a major global public health concern.
Homoserine dehydrogenase (HSD), a key enzyme in the aspartate pathway, is a promising …

Deciphering the function of new gonococcal vaccine antigens using phenotypic microarrays

BI Baarda, S Emerson, PJ Proteau… - Journal of …, 2017 - Am Soc Microbiol
The function and extracellular location of cell envelope proteins make them attractive
candidates for developing vaccines against bacterial diseases, including challenging drug …

[HTML][HTML] An immunoproteomics study of antisera from patients with gonorrhea identifies novel Neisseria gonorrhoeae proteins

A Dijokaite-Guraliuc, MV Humbert, P Skipp… - Frontiers in …, 2023 - frontiersin.org
Background Neisseria gonorrhoeae (gonococcus) is the causative agent of the sexually
transmitted disease gonorrhea, for which no vaccines exist. Efforts are being made to …

[PDF][PDF] O desenvolvimento de vacinas contra COVID-19 no primeiro ano da pandemia: um estudo narrativo

ASB OLIVEIRA, D Andolfatto… - Revista de Atenção à …, 2022 - seer.uscs.edu.br
Introdução: em dezembro de 2019 uma nova doença surgiu em Wuhan (China) e em 11 de
março de 2020 o mundo passou a presenciar o início de uma pandemia que, para muitos …