Intergenerational transmission of trauma effects: putative role of epigenetic mechanisms

R Yehuda, A Lehrner - World psychiatry, 2018 - Wiley Online Library
This paper reviews the research evidence concerning the intergenerational transmission of
trauma effects and the possible role of epigenetic mechanisms in this transmission. Two …

A meta-analysis of maternal prenatal depression and anxiety on child socioemotional development

S Madigan, H Oatley, N Racine, RMP Fearon… - Journal of the American …, 2018 - Elsevier
Objective Observed associations between maternal prenatal stress and children's
socioemotional development have varied widely in the literature. The objective of the current …

[PDF][PDF] The prevalence of adverse childhood experiences, nationally, by state, and by race or ethnicity

V Sacks, D Murphey - Child trends, 2018 - virtualeduc.com
A growing body of research has made it increasingly apparent that adverse childhood
experiences (ACEs) are a critical public health issue. ACEs are potentially traumatic …

Pregnancy as a period of risk, adaptation, and resilience for mothers and infants

EP Davis, AJ Narayan - Development and psychopathology, 2020 - cambridge.org
The pregnancy period represents a unique window of opportunity to identify risks to both the
fetus and mother and to deter the intergenerational transmission of adversity and mental …

Life course approaches to the causes of health disparities

NL Jones, SE Gilman, TL Cheng… - … journal of public …, 2019 - ajph.aphapublications.org
Reducing health disparities requires an understanding of the mechanisms that generate
disparities. Life course approaches to health disparities leverage theories that explain how …

Maternal IL-6 during pregnancy can be estimated from newborn brain connectivity and predicts future working memory in offspring

MD Rudolph, AM Graham, E Feczko… - Nature …, 2018 - nature.com
Several lines of evidence support the link between maternal inflammation during pregnancy
and increased likelihood of neurodevelopmental and psychiatric disorders in offspring. This …

[HTML][HTML] Modeling gene× environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression

C Seah, MS Breen, T Rusielewicz, HN Bader… - Nature …, 2022 - nature.com
Post-traumatic stress disorder (PTSD) can develop following severe trauma, but the extent to
which genetic and environmental risk factors contribute to individual clinical outcomes is …

Maternal adverse childhood experiences, attachment style, and mental health: pathways of transmission to child behavior problems

JE Cooke, N Racine, A Plamondon, S Tough… - Child abuse & …, 2019 - Elsevier
Background Investigations have found mothers' adverse childhood experiences (ACEs)
confer an intergenerational risk to their children's outcomes. However, mechanisms …

[HTML][HTML] Adverse childhood experiences and maternal anxiety and depression: a meta-analysis

N Racine, C Devereaux, JE Cooke, R Eirich, J Zhu… - BMC psychiatry, 2021 - Springer
Background It has been proposed that adverse childhood experiences (ACEs) can put
women at risk for mental illness in the pregnancy and postpartum periods. While some …

Maternal prenatal stress phenotypes associate with fetal neurodevelopment and birth outcomes

K Walsh, CA McCormack, R Webster… - Proceedings of the …, 2019 - National Acad Sciences
Maternal prenatal stress influences offspring neurodevelopment and birth outcomes
including the ratio of males to females born; however, there is limited understanding of what …