Rheumatoid arthritis (RA) is the most common systemic inflammatory rheumatic disease. It is
associated with significant burden at the patient and societal level. Extensive efforts have …

Abstract Type I interferons (IFN-Is) are a very important group of cytokines that are produced
by innate immune cells but also act on adaptive immune cells. IFN-Is possess antiviral …

Rheumatoid arthritis (RA) is a systemic autoimmune disease that affects about 1% of the
world's population. The etiology of RA remains unknown. It is considered to occur in the …

Rheumatoid arthritis (RA) is an autoimmune disease characterized by infiltration of immune
cells in the synovium. However, the crosstalk of immune cells and synovial fibroblasts is still …

Control of excessive mitochondrial oxidative stress could provide new targets for both
preventive and therapeutic interventions in the treatment of chronic inflammation or any …

Objectives An interferon (IFN) gene signature (IGS) is present in approximately 50% of early,
treatment naive rheumatoid arthritis (eRA) patients where it has been shown to negatively …

Rheumatoid arthritis (RA) is an autoimmune disease. The etiology of RA remains
undetermined and the pathogenesis is complex. There remains a paucity of ideal …

Rheumatoid arthritis (RA) is characterized by a tumor-like expansion of the synovium and
subsequent destruction of adjacent articular cartilage and bone. In our previous work we …

Purpose: Previous studies found that piRNAs could participate in disease progression by
regulating DNA methylation, but there are few reports on their roles in heart failure (HF) …

Purpose Rheumatoid arthritis (RA) is a disease associated with multiple factors. Epigenetics
can affect gene expression without altering the DNA sequence. In this study, we aimed to …