This review fully describes the coronavirus 3CL pro peptidomimetic inhibitors and
nonpeptidic small molecule inhibitors developed from 2010 to 2020. Specifically, the …

Bacterial infections, caused predominately by Gram-positive and Gram-negative organisms,
are proliferation of harmful strains of bacteria on or inside the body. Hospital-acquired and …

Antibiotics are commonly used to fight against bacterial infections, but bacteria have already
been resistant to almost all antibiotics due to abuse of antibiotics. 1, 2, 4-Triazole derived …

Cancer is the second leading cause of death worldwide, and it results in around 9 million
deaths annually. The anticancer agents play an intriguing role in the treatment of cancers …

In this review we compare and discuss results of compounds already reported as anticancer
agents based on isatin-derivatives, metalated as well as non-metallated. Isatin compounds …

Oxindole derivatives are known for their great interest in the field of Medicinal Chemistry, as
they display vast biological activities. Recent efforts concerning the preparation of oxindole …

Isatin (1 H indole 2, 3-dione) is a heterocyclic, endogenous lead molecule recognized in
humans and different plants. The isatin nucleus and its derivatives are owed the attention of …

The incidence of invasive bacterial infections has increased remarkably over the past two
decades, which was mainly attributed to the increasing emergence of drug-resistant bacteria …

In recent decades, several viruses have resulted in large outbreaks with serious health,
economic and social consequences. The current unprecedented outbreak of the new …

In the current medical era, human health is experiencing numerous challenges, particularly
the human malignancies. Therefore, the therapeutic arsenal for these malignancies is to be …