Pan-Genome Plasticity and Virulence Factors: A Natural Treasure Trove for Acinetobacter baumannii

T Karampatakis, K Tsergouli, P Behzadi - Antibiotics, 2024 - mdpi.com
Acinetobacter baumannii is a Gram-negative pathogen responsible for a variety of
community-and hospital-acquired infections. It is recognized as a life-threatening pathogen …

The enteric nervous system of the C. elegans pharynx is specified by the Sine oculis-like homeobox gene ceh-34

B Vidal, B Gulez, WX Cao, E Leyva-Díaz, MB Reilly… - Elife, 2022 - elifesciences.org
Overarching themes in the terminal differentiation of the enteric nervous system, an
autonomously acting unit of animal nervous systems, have so far eluded discovery. We …

Lipid transport across bacterial membranes

SI Giacometti, MR MacRae… - Annual Review of …, 2022 - annualreviews.org
The movement of lipids within and between membranes in bacteria is essential for building
and maintaining the bacterial cell envelope. Moving lipids to their final destination is often …

Very low concentration of lipopolysaccharide can induce the production of various cytokines and chemokines in human primary monocytes

R Chaiwut, W Kasinrerk - BMC research notes, 2022 - Springer
Objective Lipopolysaccharide (LPS), a component of gram-negative bacteria, is a potent
innate immune stimulus. The interaction of LPS with innate immune cells induces the …

Characterization of a glycoside hydrolase endolysin from Acinetobacter baumannii phage AbTZA1 with high antibacterial potency and novel structural features

GE Premetis, A Stathi, AC Papageorgiou… - The FEBS …, 2023 - Wiley Online Library
The classification of Acinetobacter baumannii by WHO as 'priority 1'antibiotic‐resistant
pathogen underlines the urgent need for novel antimicrobial agents towards this pathogen …

Relationship between gut microbiota and thyroid function: a two-sample Mendelian randomization study

L Xie, H Zhao, W Chen - Frontiers in Endocrinology, 2023 - frontiersin.org
Background Numerous observational studies have indicated a link between the composition
of gut microbiota and thyroid function. Nevertheless, the precise causal relationship between …

Molecular mechanisms of the anti-inflammatory effects of epigallocatechin 3-gallate (EGCG) in LPS-Activated BV-2 microglia cells

A Payne, E Taka, GM Adinew, KFA Soliman - Brain Sciences, 2023 - mdpi.com
Chronic neuroinflammation is associated with many neurodegenerative diseases, such as
Alzheimer's. Microglia are the brain's primary immune cells, and when activated, they …

Gut dysbiosis-related thrombosis in inflammatory bowel disease: Potential disease mechanisms and emerging therapeutic strategies

A Papa, P Santini, SS De Lucia, R Maresca… - Thrombosis …, 2023 - Elsevier
Patients with inflammatory bowel disease (IBD) have an increased risk of developing
venous thromboembolic events, which have a considerable impact on morbidity and …

Interactions Between Pathogenic Burkholderia and the Complement System: A Review of Potential Immune Evasion Mechanisms

I Syed, RM Wooten - Frontiers in Cellular and Infection Microbiology, 2021 - frontiersin.org
The genus Burkholderia contains over 80 different Gram-negative species including both
plant and human pathogens, the latter of which can be classified into one of two groups: the …

Antigenic operon fragmentation and diversification mechanism in Bacteroidota impacts gut metagenomics and pathobionts in Crohn's disease microlesions

NC Bank, V Singh, B McCourt, A Burberry… - Gut …, 2024 - Taylor & Francis
ABSTRACT Comensal Bacteroidota (Bacteroidota) and Enterobacteriacea are often linked
to gut inflammation. However, the causes for variability of pro-inflammatory surface antigens …