Multiple sclerosis (MS) is a central nervous system (CNS) disorder, which is mediated by an
abnormal immune response coordinated by T and B cells resulting in areas of inflammation …

Although the detailed pathogenesis of multiple sclerosis (MS) is not completely understood,
a broad range of disease-modifying therapies (DMTs) are available. A common side effect of …

Objective To investigate the results of real-world application of non-myeloablative
autologous HSCT for multiple sclerosis (MS). Methods Between July 2003 and October …

Information exchange is essential for the brain, where it communicates the physiological and
pathological signals to the periphery and vice versa. Extracellular vesicles (EVs) are a …

Abstract Purpose of Review Autologous haematopoietic stem cell transplantation (AHSCT)
is increasingly considered a treatment option for patients with multiple sclerosis (MS), an …

Development of disease-modifying therapies including monoclonal antibody (mAb)-based
therapeutics for the treatment of multiple sclerosis (MS) has been extremely successful over …

Background Optic neuritis (ON) is frequently encountered in multiple sclerosis, neuromyelitis
optica spectrum disorder, anti-myelin oligodendrocyte glycoprotein associated disease, and …

Autoimmune diseases (ADs) are characterized by loss of immune tolerance, high chronicity,
with substantial morbidity and mortality, despite conventional immunosuppression (IS) or …

Over the past decades, hematopoietic stem cell transplantation (HSCT) has been evolving
as specific treatment for patients with severe and refractory autoimmune diseases (ADs) …

Background: Since the 1990s, transplantations of hematopoietic and mesenchymal stem
cells (HSCT and MSCT) and dendritic cell (DCT) have been investigated for the treatment of …