Secure and robust cloud computing for high-throughput forensic microsatellite sequence analysis and databasing

SF Bailey, MK Scheible, C Williams, DSBS Silva… - Forensic Science …, 2017 - Elsevier
Next-generation Sequencing (NGS) is a rapidly evolving technology with demonstrated
benefits for forensic genetic applications, and the strategies to analyze and manage the …

[HTML][HTML] Flanking variation influences rates of stutter in simple repeats

AE Woerner, JL King, B Budowle - Genes, 2017 - mdpi.com
It has been posited that the longest uninterrupted stretch (LUS) of tandem repeats, as
defined by the number of exactly matching repeating motif units, is a better predictor of rates …

Assessment of impact of DNA extraction methods on analysis of human remain samples on massively parallel sequencing success

X Zeng, K Elwick, C Mayes, M Takahashi… - International journal of …, 2019 - Springer
Skeletal remains recovered from missing persons' cases are often exposed to harsh
environmental conditions resulting in the DNA being damaged, degraded, and/or the …

[HTML][HTML] Recombulator-X: A fast and user-friendly tool for estimating X chromosome recombination rates in forensic genetics

S Aneli, P Fariselli, E Chierto, C Bini… - PLOS Computational …, 2023 - journals.plos.org
Genetic markers (especially short tandem repeats or STRs) located on the X chromosome
are a valuable resource to solve complex kinship cases in forensic genetics in addition or …

Genetic analysis of Southern Brazil subjects using the PowerSeq™ AUTO/Y system for short tandem repeat sequencing

DSBS Silva, FR Sawitzki, MKR Scheible… - Forensic Science …, 2018 - Elsevier
With the advent of Next-Generation Sequencing technology, sequencing of short tandem
repeats (STRs) allows for a more detailed analysis when compared to size-based fragment …

A scalable parallel algorithm for global sequence alignment with customizable scoring scheme

MU Sadiq, MM Yousaf - Concurrency and Computation …, 2023 - Wiley Online Library
Sequence alignment is a critical computational problem in various domains, including
genomics, proteomics, and natural language processing. The Needleman‐Wunsch (NW) …

Massively parallel sequencing of 10 autosomal STRs in Chinese using the ion torrent personal genome machine (PGM)

X Zhao, H Li, Z Wang, K Ma, Y Cao, W Liu - Forensic Science International …, 2016 - Elsevier
Massively parallel sequencing (MPS) technology is gaining interest in the forensic
community. The capabilities of high throughput and simultaneously analyses of many …

[HTML][HTML] Assessing the performance of quantity and quality metrics using the QIAGEN Investigator® Quantiplex® pro RGQ kit

J Morrison, S McColl, J Louhelainen, K Sheppard… - Science & Justice, 2020 - Elsevier
Abstract The Quantiplex® Pro RGQ kit quantifies DNA in a sample, supports the detection of
mixtures and assesses the extent of DNA degradation based on relative ratios of amplified …

Massive parallel sequencing of short tandem repeats in the Korean population

SY Kim, HC Lee, U Chung, SK Ham, HY Lee… - …, 2018 - Wiley Online Library
STR analysis using capillary electrophoresis has been the most widely used method for
forensic DNA typing. Recently, massive parallel sequencing (MPS) technique has been …

[HTML][HTML] Concordance and characterization of massively parallel sequencing at 58 STRs in a Tibetan population

H Li, C Zhang, G Song, K Ma, Y Cao… - Molecular Genetics & …, 2021 - ncbi.nlm.nih.gov
Background Massively parallel sequencing (MPS) is a promising supplementary method for
forensic casework in short tandem repeats (STRs) genotyping, owing to several …