We performed a systematic literature review and narrative synthesis according to a pre‐
registered protocol (Prospero: CRD42022376561) to identify the evidence associated with …

Normal brain function requires a tightly regulated balance between excitatory and inhibitory
neurotransmissions. γ‐Aminobutyric acid type A (GABAA) receptors represent the major …

Alzheimer's disease (AD) and epilepsy are common neurological disorders in the elderly. A
bi-directional link between these neurological diseases has been reported, with patients …

Objective To evaluate whether fenfluramine (FFA) is associated with improvement in
everyday executive function (EF)—self-regulation—in preschool-aged children with Dravet …

Objectives To compare the efficacy and safety of antiseizure medications (ASMs), both as
monotherapies and adjunctive therapies, for idiopathic generalized epilepsies (IGEs) and …

Generalized epilepsy affects 24 million people globally; at least 25% of cases remain
medically refractory. The thalamus, with widespread connections throughout the brain, plays …

Background Antiseizure medication (ASM) as monotherapy or in combination is the
treatment of choice for most patients with epilepsy. Therefore, knowledge about the typical …

Introduction Lacosamide is licensed for the treatment of focal seizures in both adults and
children, however there is little information available on its adverse reactions. Using the FDA …

Background This study measured sleep quality among caregivers of patients with Dravet
syndrome (DS) and assessed the impacts of mental health problems and caregiver burden …

Introduction: Cognitive impairment is a common complication and comorbidity of diabetes.
However, the underlying mechanisms of diabetes-associated cognitive dysfunction are …