Oxygen battle in the gut: Hypoxia and hypoxia-inducible factors in metabolic and inflammatory responses in the intestine

R Singhal, YM Shah - Journal of Biological Chemistry, 2020 - ASBMB
The gastrointestinal tract is a highly proliferative and regenerative tissue. The intestine also
harbors a large and diverse microbial population collectively called the gut microbiome …

CAR-T regulatory (CAR-Treg) cells: engineering and applications

M Arjomandnejad, AL Kopec, AM Keeler - Biomedicines, 2022 - mdpi.com
Regulatory T cells are critical for maintaining immune tolerance. Recent studies have
confirmed their therapeutic suppressive potential to modulate immune responses in organ …

Association between intestinal microbiota and inflammatory bowel disease

Y Zhang, X Si, L Yang, H Wang… - Animal models and …, 2022 - Wiley Online Library
Inflammatory bowel disease (IBD), which includes Crohn's disease (CD) and ulcerative
colitis (UC), has emerged as a global disease with high incidence, long duration …

Regulation of oxygen homeostasis at the intestinal epithelial barrier site

Š Konjar, M Pavšič, M Veldhoen - International journal of molecular …, 2021 - mdpi.com
The unique biology of the intestinal epithelial barrier is linked to a low baseline oxygen
pressure (pO2), characterised by a high rate of metabolites circulating through the intestinal …

Epidemiology, burden of disease, and unmet needs in the treatment of ulcerative colitis in Asia

SC Wei, J Sollano, YT Hui, W Yu… - Expert Review of …, 2021 - Taylor & Francis
Introduction Ulcerative colitis (UC) is an idiopathic, chronic inflammatory disease of the
colon, characterized by relapsing and remitting symptoms. Although traditionally viewed as …

A novel probiotic combination ameliorates Crohn's disease–like ileitis by increasing short-chain fatty acid production and modulating essential adaptive immune …

L Di Martino, A Osme, M Ghannoum… - Inflammatory Bowel …, 2023 - academic.oup.com
BACKGROUND Crohn's disease (CD) represents a significant public health challenge. We
identified a combination of beneficial probiotic strains (Saccharomyces boulardii …

[HTML][HTML] Project: clinical guidelines for the diagnostics and treatment of ulcerative colitis

VT Ivashkin, YA Shelygin, EA Belousova… - …, 2019 - ruproctology.com
PROJECT: CLINICAL GUIDELINES FOR THE DIAGNOSTICS AND TREATMENT OF
ULCERATIVE COLITIS | Ivashkin | Koloproktologia Koloproktologia Koloproktologiâ eng …

Symptoms and symptom clusters in patients newly diagnosed with inflammatory bowel disease: results from the IBSEN III Study

I Johansen, MC Småstuen, ST Løkkeberg… - BMC …, 2023 - Springer
Background Patients with inflammatory bowel disease report multiple symptoms, but the
relationships among co-occurring symptoms are poorly understood. This study aimed to …

Association between dietary factors and constipation in adults living in Luxembourg and taking part in the ORISCAV-LUX 2 survey

M Rollet, T Bohn, F Vahid, ORISCAV Working Group - Nutrients, 2021 - mdpi.com
Constipation, a disorder of bowel movements, is among the most frequent gastrointestinal
complaints in Western countries. Dietary constituents such as inadequate fiber intake have …

Alginate-based drug carrier systems to target inflammatory bowel disease: a review

D Swastha, N Varsha, S Aravind, KB Samyuktha… - International Journal of …, 2023 - Elsevier
Inflammatory bowel disease (IBD) is an inflammatory disorder that affects the gastrointestinal
tract. IBD has become an increasingly common condition in both developed and developing …