Background Concern about estrogen‐related adverse effects has led to progressive
reductions in the estrogen dose in combination oral contraceptives (COCs). However …

Gaubius Laboratory TNO-PG, Leiden, The Netherlands! ntroduction minimal changes
(avoiding the interpretation)(8). During the second meeting in Amsterdam in 1995 it was …

Hereditary angioedema (HAE), a rare but life-threatening condition, manifests as acute
attacks of facial, laryngeal, genital, or peripheral swelling or abdominal pain secondary to …

Combined oral contraceptives (OC) are known to increase the risk of venous
thromboembolism. The aim of this randomized, cycle-controlled, cross-over study in 28 …

OBJECTIVE: Fluctuations in sex hormones can trigger angioedema attacks in women with
hereditary angioedema. Combined oral contraceptive therapies, as well as pregnancy, can …

Objective To compare the impact on thrombin generation of the new combined oral
contraceptive containing 15 mg estetrol and 3 mg drospirenone with ethinylestradiol (30 or …

Dienogest (DNG) is a 19-nortestosterone derivative (a C-19 progestogen) with a
cyanomethyl instead of an ethinyl group at the C-17 position, which may make the …

This is the first double-blind, controlled, randomized study comparing the effect of different
estrogen components in oral contraceptives (OCs) on hemostasis variables. Four groups of …

Women with hereditary angioedema (HAE) are more likely to be symptomatic that men.
Hormonal factors (puberty, contraception, pregnancy,....) play a significant role in the …

Hereditary angioedema (HAE) is a rare autosomal dominant disease, with patients often
suffering with associated symptoms for many years before receiving a correct diagnosis. The …