Diagnostic, prognostic, and therapeutic significance of long non-coding RNA MALAT1 in cancer

B Goyal, SRM Yadav, N Awasthee, S Gupta… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Abstract Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1) is a widely
studied lncRNA in cancer. Although dispensable for normal physiology, MALAT1 is …

Biomolecular condensates and cancer

A Boija, IA Klein, RA Young - Cancer cell, 2021 - cell.com
Malignant transformation is characterized by dysregulation of diverse cellular processes that
have been the subject of detailed genetic, biochemical, and structural studies, but only …

DirectRMDB: a database of post-transcriptional RNA modifications unveiled from direct RNA sequencing technology

Y Zhang, J Jiang, J Ma, Z Wei, Y Wang… - Nucleic Acids …, 2023 - academic.oup.com
With advanced technologies to map RNA modifications, our understanding of them has
been revolutionized, and they are seen to be far more widespread and important than …

The functions and clinical application potential of exosomes derived from adipose mesenchymal stem cells: a comprehensive review

P Hong, H Yang, Y Wu, K Li, Z Tang - Stem cell research & therapy, 2019 - Springer
Exosomes are extracellular membranous nanovesicles that mediate local and systemic
intercellular communication by transporting proteins or nucleic acids (DNA and RNA) into …

MALAT1: A key regulator in lung cancer pathogenesis and therapeutic targeting

AA Bhat, O Afzal, M Afzal, G Gupta, R Thapa… - … -Research and Practice, 2023 - Elsevier
Lung cancer remains a formidable global health burden, necessitating a comprehensive
understanding of the underlying molecular mechanisms driving its progression. Recently …

Long non-coding RNAs regulate drug resistance in cancer

K Liu, L Gao, X Ma, JJ Huang, J Chen, L Zeng… - Molecular cancer, 2020 - Springer
Chemoresistance, whether intrinsic or acquired, is a major obstacle in the treatment of
cancer. The resistance of cancer cells to chemotherapeutic drugs can result from various …

MALAT1-related signaling pathways in colorectal cancer

WW Xu, J Jin, X Wu, QL Ren, M Farzaneh - Cancer cell international, 2022 - Springer
Colorectal cancer (CRC) is one of the most lethal and prevalent solid malignancies
worldwide. There is a great need of accelerating the development and diagnosis of CRC …

Regulatory networks of LncRNA MALAT-1 in cancer

S Fu, Y Wang, H Li, L Chen, Q Liu - Cancer management and …, 2020 - Taylor & Francis
Long noncoding (lnc) RNAs are a group of RNAs with a length greater than 200 nt that do
not encode a protein but play an essential role in regulating the expression of target genes …

Long non-coding RNA MALAT1 promotes angiogenesis and immunosuppressive properties of HCC cells by sponging miR-140

ZH Hou, XW Xu, XY Fu, LD Zhou… - American Journal of …, 2020 - journals.physiology.org
Hepatocellular carcinoma (HCC) is the most prevalent primary liver cancer in adults.
Previous studies in our laboratory found that long non-coding RNA metastasis-associated …

Roles of lncRNAs in cancer: Focusing on angiogenesis

KT Jin, JY Yao, XL Fang, H Di, YY Ma - Life sciences, 2020 - Elsevier
Approximately 98% of the human genome consists of non-coding sequences that are
classified into two classes by size: small non-coding RNAs (≤ 200 nucleotides) and long …