Surfactant protein D (SP-D) is a multimeric collectin that is involved in innate immune
defense and expressed in pulmonary, as well as non-pulmonary, epithelia. SP-D exerts …

The lung interfaces with the environment across a continuous epithelium composed of
various cell types along the proximal and distal airways. At the alveolar structure level, the …

Surfactant proteins, SP-A and SP-D, are collagen-containing C-type (calcium dependent)
lectins called collectins, which contribute significantly to surfactant homeostasis and …

The rapid development of nanotechnology is opening a huge world of promising
possibilities in healthcare, but this is also increasing the necessity to study the potential risk …

IL-10 can be considered an important agent in the resolution of inflammation. Originally
named “cytokine synthesis inhibitory factor” for its ability to inhibit IFN-γ and IL-2 production …

Over recent years the research focus within the field of respiratory drug delivery has
broadened to include a wide range of potential applications for inhalation by delivering …

Surfactant proteins A (SP-A) and D (SP-D) have been implicated in pulmonary innate
immunity. The proteins are host defense lectins, belonging to the collectin family which also …

Background Asthma is a complex inflammatory disease which affects multiple individuals
worldwide especially pediatric ages. Aims This study aimed to assess the possible …

The acute inflammatory airway response is characterized by a time-dependent onset
followed by active resolution. Emerging evidence suggests that epithelial cells of the …

Background IL-10 is a cytokine mainly produced by macrophages that plays key roles in
tolerance to inhaled antigens and in lung homeostasis. Its regulation in alveolar …