HOXA9 transcription factor is a double-edged sword: from development to cancer progression
The HOXA9 transcription factor serves as a molecular orchestrator in cancer stemness,
epithelial-mesenchymal transition (EMT), metastasis, and generation of the tumor …
epithelial-mesenchymal transition (EMT), metastasis, and generation of the tumor …
Resolving the hematopoietic stem cell state by linking functional and molecular assays
M Jassinskaja, M Gonka, DG Kent - Blood, 2023 - ashpublications.org
One of the most challenging aspects of stem cell research is the reliance on retrospective
assays for ascribing function. This is especially problematic for hematopoietic stem cell …
assays for ascribing function. This is especially problematic for hematopoietic stem cell …
A novel t(X;21)(p11.4;q22.12) translocation adds to the role of BCOR and RUNX1 in myelodysplastic syndromes and acute myeloid leukemias
E Mavridou, AG Lema Fernandez… - Genes …, 2024 - Wiley Online Library
In myeloid neoplasms, both fusion genes and gene mutations are well‐established events
identifying clinicopathological entities. In this study, we present a thus far undescribed t (X; …
identifying clinicopathological entities. In this study, we present a thus far undescribed t (X; …
Order-of-mutation effects on cancer progression: models for myeloproliferative neoplasm
In some patients with myeloproliferative neoplasms (MPN), two genetic mutations are often
found: JAK2 V617F and one in the TET2 gene. Whether one mutation is present influences …
found: JAK2 V617F and one in the TET2 gene. Whether one mutation is present influences …
Exploring the expression and clinical significance of the miR-140-3p-HOXA9 axis in colorectal cancer
W Cui, X Bai, Z Bai, F Chen, J Xu, W Bai… - Journal of Cancer …, 2024 - Springer
Purpose This study aims to investigate the expression patterns and clinical significance of
miR-140-3p and homeobox A9 (HOXA9) in colorectal cancer (CRC) selected by …
miR-140-3p and homeobox A9 (HOXA9) in colorectal cancer (CRC) selected by …
Determine transposable genes when the orders of genes are different
Y Wang - bioRxiv, 2023 - biorxiv.org
Certain nucleotide sequences in DNA can change their positions. Such nucleotide
sequences might be shorter than a general gene. When we restrict to nucleotide sequences …
sequences might be shorter than a general gene. When we restrict to nucleotide sequences …
A Bioinformatics Analysis of circRNA/miRNA/mRNA Interactions in Acute Myeloid Leukemia
Objective: Acute myeloid leukemia (AML) is a lethal type of cancer associated with
dysregulation of progenitor hematopoietic stem cell behavior and its incidence is …
dysregulation of progenitor hematopoietic stem cell behavior and its incidence is …