Mitochondria and brain disease: a comprehensive review of pathological mechanisms and therapeutic opportunities

VJ Clemente-Suárez, L Redondo-Flórez… - Biomedicines, 2023 - mdpi.com
Mitochondria play a vital role in maintaining cellular energy homeostasis, regulating
apoptosis, and controlling redox signaling. Dysfunction of mitochondria has been implicated …

Mitochondrial dysfunction at the crossroad of cardiovascular diseases and cancer

C Rocca, T Soda, EM De Francesco, M Fiorillo… - Journal of Translational …, 2023 - Springer
A large body of evidence indicates the existence of a complex pathophysiological
relationship between cardiovascular diseases and cancer. Mitochondria are crucial …

Mitochondrial dysfunction and sarcopenic obesity: the role of exercise

S Hadjispyrou, A Giannopoulos, A Philippou… - Journal of Clinical …, 2023 - mdpi.com
Sarcopenic obesity (SO) constitutes the coexistence of skeletal muscle mass loss
(sarcopenia) and excess adiposity (obesity). It is mainly considered as a condition in the …

[HTML][HTML] Sex differences in frailty among older adults

RS Zeidan, T McElroy, L Rathor, MS Martenson… - Experimental …, 2023 - Elsevier
By definition, aging is a natural, gradual and continuous process. On the other hand, frailty
reflects the increase in vulnerability to stressors and shortens the time without disease …

Associations of the MIND diet with cardiometabolic diseases and their risk factors: a systematic review

Z Akbar, S Fituri, A Ouagueni, J Alalwani… - Diabetes, Metabolic …, 2023 - Taylor & Francis
Purpose Recent studies have expanded the scope of research on the Mediterranean-DASH
Intervention for Neurodegenerative Delay (MIND) diet beyond its impact on cognitive …

Toward exercise guidelines for optimizing fat oxidation during exercise in obesity: A systematic review and meta-regression

IA Chavez-Guevara, FJ Amaro-Gahete… - Sports Medicine, 2023 - Springer
Background Exercise training performed at maximal fat oxidation (FATmax) is an efficient
non-pharmacological approach for the management of obesity and its related cardio …

Elevated parkinsonism pathological markers in dopaminergic neurons with developmental exposure to atrazine

H Zhao, J Xie, S Wu, X Zhao, OF Sánchez, S Min… - Science of The Total …, 2024 - Elsevier
Atrazine (ATZ) is one of the most used herbicides in the US and a known endocrine
disruptor. ATZ is frequently detected in drinking water, especially in Midwestern regions of …

Small-molecule redox modulators with anticancer activity: A comprehensive mechanistic update

C Pal - Free Radical Biology and Medicine, 2023 - Elsevier
The pursuit of effective anticancer therapies has led to a burgeoning interest in the realm of
redox modulation. This review provides a comprehensive exploration of the intricate …

Mitochondrial dysfunction and coenzyme Q10 supplementation in post-viral fatigue syndrome: an overview

D Mantle, IP Hargreaves, JC Domingo… - International Journal of …, 2024 - mdpi.com
Post-viral fatigue syndrome (PVFS) encompasses a wide range of complex neuroimmune
disorders of unknown causes characterised by disabling post-exertional fatigue, myalgia …

Gut Microbiota and Mitochondria: Health and Pathophysiological Aspects of Long COVID

LM Ailioaie, C Ailioaie, G Litscher - International Journal of Molecular …, 2023 - mdpi.com
The current understanding of long COVID (LC) is still limited. This review highlights key
findings regarding the role of gut microbiota, mitochondria, and the main pathophysiological …