[HTML][HTML] Polypharmacy, inappropriate prescribing, and deprescribing in older people: through a sex and gender lens

PA Rochon, M Petrovic, A Cherubini… - The Lancet Healthy …, 2021 - thelancet.com
Polypharmacy is very common in older adults and increases the risk of inappropriate and
unsafe prescribing for older adults. Older adults, particularly women (who make up the …

[HTML][HTML] Adverse drug reactions in older adults: a narrative review of the literature

MB Zazzara, K Palmer, DL Vetrano, A Carfì… - European geriatric …, 2021 - Springer
Abstract Purpose Adverse drug reactions (ADRs) represent a common and potentially
preventable cause of unplanned hospitalization, increasing morbidity, mortality, and …

Decision making for older adults with multiple chronic conditions: executive summary for the American Geriatrics Society guiding principles on the care of older adults …

C Boyd, CD Smith, FA Masoudi… - Journal of the …, 2019 - Wiley Online Library
Caring for older adults with multiple chronic conditions (MCCs) is challenging. The American
Geriatrics Society (AGS) previously developed The AGS Guiding Principles for the Care of …

The challenge of HIV treatment in an era of polypharmacy

D Back, C Marzolini - Journal of the International AIDS Society, 2020 - Wiley Online Library
Introduction The availability of potent antiretroviral therapy has transformed HIV infection into
a chronic disease such that people living with HIV (PLWH) have a near normal life …

Deprescribing in older adults with cardiovascular disease

A Krishnaswami, MA Steinman, P Goyal… - Journal of the American …, 2019 - jacc.org
Deprescribing, an integral component of a continuum of good prescribing practices, is the
process of medication withdrawal or dose reduction to correct or prevent medication-related …

Sodium glucose cotransporter 2 inhibitors and risk of genital mycotic and urinary tract infection: a population‐based study of older women and men with diabetes

IC Lega, SE Bronskill, MA Campitelli… - Diabetes, Obesity …, 2019 - Wiley Online Library
Aims The objective of the study was to quantify the association between SGLT2 inhibitors
and genital mycotic infection and between SGLT2 inhibitors and urinary tract infection (UTI) …

Polypharmacy, potentially inappropriate medications, and drug-drug interactions in vulnerable older adults with advanced cancer initiating cancer treatment

E Ramsdale, M Mohamed, V Yu, E Otto, K Juba… - The …, 2022 - academic.oup.com
Purpose Polypharmacy is prevalent in older adults starting cancer treatment and associated
with potentially inappropriate medications (PIM), potential drug-drug interactions (DDI), and …

Evaluation of a common prescribing cascade of calcium channel blockers and diuretics in older adults with hypertension

RD Savage, JD Visentin, SE Bronskill… - JAMA internal …, 2020 - jamanetwork.com
Importance Calcium channel blockers (CCBs) are commonly prescribed agents for
hypertension that can cause peripheral edema. A prescribing cascade occurs when the …

[HTML][HTML] Associations between polypharmacy, symptom burden, and quality of life in patients with advanced, life-limiting illness

Y Schenker, SY Park, K Jeong, J Pruskowski… - Journal of general …, 2019 - Springer
Background Polypharmacy may be particularly burdensome near the end of life, as patients
“accumulate” medications to treat and prevent multiple diseases. Objective To evaluate …

Facing the challenge of polypharmacy when prescribing for older people with cardiovascular disease. A review by the European Society of Cardiology Working Group …

J Tamargo, KP Kjeldsen, E Delpón… - European Heart …, 2022 - academic.oup.com
Population ageing has resulted in an increasing number of older people living with chronic
diseases (multimorbidity) requiring five or more medications daily (polypharmacy). Ageing …