Single and multi-functional coating strategies for enhancing the biocompatibility and tissue integration of blood-contacting medical implants

M Badv, F Bayat, JI Weitz, TF Didar - Biomaterials, 2020 - Elsevier
Device-associated clot formation and poor tissue integration are ongoing problems with
permanent and temporary implantable medical devices. These complications lead to …

[HTML][HTML] Future perspectives in small-diameter vascular graft engineering

P Mallis, A Kostakis, C Stavropoulos-Giokas… - Bioengineering, 2020 - mdpi.com
The increased demands of small-diameter vascular grafts (SDVGs) globally has forced the
scientific society to explore alternative strategies utilizing the tissue engineering …

[HTML][HTML] Functionalization of in vivo tissue-engineered living biotubes enhance patency and endothelization without the requirement of systemic anticoagulant …

H Yan, Q Cheng, J Si, S Wang, Y Wan, X Kong… - Bioactive Materials, 2023 - Elsevier
Vascular regeneration and patency maintenance, without anticoagulant administration,
represent key developmental trends to enhance small-diameter vascular grafts (SDVG) …

[HTML][HTML] Biocompatibility pathways and mechanisms for bioactive materials: The bioactivity zone

DF Williams - Bioactive Materials, 2022 - Elsevier
This essay analyzes the scientific evidence that forms the basis of bioactive materials,
covering the fundamental understanding of bioactivity phenomena and correlation with the …

[HTML][HTML] TPU-based antiplatelet cardiovascular prostheses prepared using fused deposition modelling

J Domínguez-Robles, E Utomo, VA Cornelius… - Materials & Design, 2022 - Elsevier
This work describes the use of fused deposition modelling (FDM) to prepare antiplatelet
thermoplastic polyurethane (TPU)-based tubular grafts. FDM 3D-printing technology is …

[HTML][HTML] Fabrication of strong, bioactive vascular grafts with PCL/collagen and PCL/silica bilayers for small-diameter vascular applications

S Park, J Kim, MK Lee, C Park, HD Jung, HE Kim… - Materials & Design, 2019 - Elsevier
In vascular surgical applications, small-diameter vascular grafts made from synthetic
polymers are rarely commercialized, owing to delayed reendothelialization and subsequent …

[HTML][HTML] Tissue-engineered small-diameter vascular grafts containing novel copper-doped bioactive glass biomaterials to promote angiogenic activity and endothelial …

N Alasvand, A Behnamghader, PB Milan, S Simorgh… - Materials Today Bio, 2023 - Elsevier
Small-diameter vascular grafts frequently fail because of obstruction and infection. Despite
the wide range of commercially available vascular grafts, the anatomical uniqueness of …

[HTML][HTML] Tissue engineering of small-diameter vascular grafts and their in vivo evaluation in large animals and humans

S Fang, DG Ellman, DC Andersen - Cells, 2021 - mdpi.com
To date, a wide range of materials, from synthetic to natural or a mixture of these, has been
explored, modified, and examined as small-diameter tissue-engineered vascular grafts (SD …

Drug loaded implantable devices to treat cardiovascular disease

M Adhami, NK Martin, C Maguire… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction It is widely acknowledged that cardiovascular diseases (CVDs) continue to be
the leading cause of death globally. Furthermore, CVDs are the leading cause of diminished …

Surface modification of polytetrafluoroethylene (PTFE) with a heparin-immobilized extracellular matrix (ECM) coating for small-diameter vascular grafts applications

C Yu, H Yang, L Wang, JA Thomson, LS Turng… - Materials Science and …, 2021 - Elsevier
Intimal hyperplasia, thrombosis formation, and delayed endothelium regeneration are the
main causes that restrict the clinical applications of PTFE small-diameter vascular grafts …