Placental function and the development of fetal overgrowth and fetal growth restriction

JH Dumolt, TL Powell… - Obstetrics and Gynecology …, 2021 - obgyn.theclinics.com
The developing fetus undergoes a dynamic period of rapid growth that is responsive to
changes in the in utero environment that may contribute to the development of fetal growth …

Personalized nutrition approach in pregnancy and early life to tackle childhood and adult non-communicable diseases

S Alabduljabbar, SA Zaidan, AP Lakshmanan… - Life, 2021 - mdpi.com
The development of childhood and adult non-communicable diseases (NCD) is associated
with environmental factors, starting from intrauterine life. A new theory finds the roots of …

Maternal lipid levels across pregnancy impact the umbilical cord blood lipidome and infant birth weight

JL LaBarre, M Puttabyatappa, PXK Song… - Scientific reports, 2020 - nature.com
Major alterations in metabolism occur during pregnancy enabling the mother to provide
adequate nutrients to support infant development, affecting birth weight (BW) and potentially …

Effects of maternal obesity on placental phenotype

AL Fowden, EJ Camm… - Current Vascular …, 2021 - ingentaconnect.com
The incidence of obesity is rising rapidly worldwide with the consequence that more women
are entering pregnancy overweight or obese. This leads to an increased incidence of clinical …

A potential role for lysophosphatidylcholine in the delivery of long chain polyunsaturated fatty acids to the fetal circulation

V Ferchaud-Roucher, A Kramer, E Silva… - … et Biophysica Acta (BBA …, 2019 - Elsevier
The mechanisms of placental transfer of long chain polyunsaturated fatty acids are poorly
understood, however fatty acid transporters in the syncytiotrophoblast microvillous (MVM) …

Nutritional lifestyle intervention in obese pregnant women, including lower carbohydrate intake, is associated with increased maternal free fatty acids, 3-β …

J Harreiter, D Simmons, G Desoye, R Corcoy… - Diabetes …, 2019 - Am Diabetes Assoc
OBJECTIVE In our randomized controlled trial, we investigated the impact of healthy eating
(HE) aiming for restricted gestational weight gain (GWG) and physical activity (PA) …

Serum metabolic profiles of chinese women with perimenopausal obesity explored by the untargeted metabolomics approach

S Ding, M Chen, Y Liao, Q Chen, X Lin… - Frontiers in …, 2021 - frontiersin.org
By far, no study has focused on observing the metabolomic profiles in perimenopause-
related obesity. This study attempted to identify the metabolic characteristics of subjects with …

Maternal obesity alters placental lysophosphatidylcholines, lipid storage, and the expression of genes associated with lipid metabolism

KL Bidne, AL Rister, AR McCain, BD Hitt… - Biology of …, 2021 - academic.oup.com
Dyslipidemia is a characteristic of maternal obesity and previous studies have demonstrated
abnormalities in fatty acid oxidation and storage in term placentas. However, there is little …

The impact of maternal body composition and dietary fat consumption upon placental lipid processing and offspring metabolic health

ZJW Easton, TRH Regnault - Nutrients, 2020 - mdpi.com
The proportion of women of reproductive age who are overweight or obese is increasing
globally. Gestational obesity is strongly associated in both human studies and animal …

Towards an optimized fetal DHA accretion: differences on maternal DHA supplementation using phospholipids vs. triglycerides during pregnancy in different models

A Gázquez, E Larqué - Nutrients, 2021 - mdpi.com
Docosahexaenoic acid (DHA) supplementation during pregnancy has been recommended
by several health organizations due to its role in neural, visual, and cognitive development …