The immune response in tuberculosis

A O'Garra, PS Redford, FW McNab… - Annual review of …, 2013 - annualreviews.org
There are 9 million cases of active tuberculosis reported annually; however, an estimated
one-third of the world's population is infected with Mycobacterium tuberculosis and remains …

[HTML][HTML] Human tuberculosis and Mycobacterium tuberculosis complex: A review on genetic diversity, pathogenesis and omics approaches in host biomarkers …

RD Kanabalan, LJ Lee, TY Lee, PP Chong… - Microbiological …, 2021 - Elsevier
Mycobacterium tuberculosis complex (MTBC) refers to a group of mycobacteria
encompassing nine members of closely related species that causes tuberculosis in animals …

Official American Thoracic Society/Infectious Diseases Society of America/Centers for Disease Control and Prevention clinical practice guidelines: diagnosis of …

DM Lewinsohn, MK Leonard, PA LoBue… - Clinical Infectious …, 2017 - academic.oup.com
Abstract Background. Individuals infected with Mycobacterium tuberculosis (Mtb) may
develop symptoms and signs of disease (tuberculosis disease) or may have no clinical …

Laboratory diagnosis of tuberculosis in resource-poor countries: challenges and opportunities

LM Parsons, Á Somoskövi, C Gutierrez… - Clinical microbiology …, 2011 - Am Soc Microbiol
With an estimated 9.4 million new cases globally, tuberculosis (TB) continues to be a major
public health concern. Eighty percent of all cases worldwide occur in 22 high-burden, mainly …

Interferon-γ release assays for the diagnosis of active tuberculosis: a systematic review and meta-analysis

M Sester, G Sotgiu, C Lange, C Giehl… - European …, 2011 - Eur Respiratory Soc
Interferon-γ release assays (IGRAs) are now established for the immunodiagnosis of latent
infection with Mycobacterium tuberculosis in many countries. However, the role of IGRAs for …

[HTML][HTML] Blood transcriptomics reveal the evolution and resolution of the immune response in tuberculosis

O Tabone, R Verma, A Singhania… - Journal of Experimental …, 2021 - rupress.org
Blood transcriptomics have revealed major characteristics of the immune response in active
TB, but the signature early after infection is unknown. In a unique clinically and temporally …

[HTML][HTML] Evolution of machine learning in tuberculosis diagnosis: a review of deep learning-based medical applications

M Singh, GV Pujar, SA Kumar, M Bhagyalalitha… - Electronics, 2022 - mdpi.com
Tuberculosis (TB) is an infectious disease that has been a major menace to human health
globally, causing millions of deaths yearly. Well-timed diagnosis and treatment are an arch …

Multifunctional CD4+ T cells correlate with active Mycobacterium tuberculosis infection

N Caccamo, G Guggino, SA Joosten… - European journal of …, 2010 - Wiley Online Library
Th1 CD4+ T cells and their derived cytokines are crucial for protection against
Mycobacterium tuberculosis. Using multiparametric flow cytometry, we have evaluated the …

International criteria for the diagnosis of ocular sarcoidosis: results of the first International Workshop On Ocular Sarcoidosis (IWOS)

CP Herbort, NA Rao, M Mochizuki… - Ocular immunology …, 2009 - Taylor & Francis
Aim: To report criteria for the diagnosis of intraocular sarcoidosis, taking into account
suggestive clinical signs and appropriate laboratory investigations and biopsy results …

Human genetics of tuberculosis: a long and winding road

L Abel, J El-Baghdadi, AA Bousfiha… - … of the Royal …, 2014 - royalsocietypublishing.org
Only a small fraction of individuals exposed to Mycobacterium tuberculosis develop clinical
tuberculosis (TB). Over the past century, epidemiological studies have shown that human …